Gene detail

AMR88_RS17595

Histidine kinase, Classic

Clostridioides difficile · GCF_002891615

ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002891615#AMR88_RS17595Stable P2CS identifier used across views.
GenomeGCF_002891615Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1785887Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_070440846.1 · MIST4 AMR88_RS17595RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa464 aa
HAMP: 170-237 aa (68 aa)1HisKA: 249-308 aa (60 aa)2HATPase_c: 355-439 aa (85 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:170:0.00000000000171:237:68:69
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw tokenHisKA:249:0.000000000442:308:61:64
3 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw tokenHATPase_c:355:0.0000000000000321:439:88:109
  • Raw architecture: HAMP:170:0.00000000000171:237:68:69#HisKA:249:0.000000000442:308:61:64#HATPase_c:355:0.0000000000000321:439:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002891615::NZ_LJCI01000028.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2617-4651Genomic interval covered by the local TCS group.
Context group IDGCF_002891615::NZ_LJCI01000028.1::G00039
Context members
AMR88_RS17595AMR88_RS17600
Partner locus tags
AMR88_RS17595AMR88_RS17600
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_070440846.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAMR88_RS17595Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_LJCI01000028.1Sequence record reported by the local genomic context database.
Genomic interval2 617-4 011 nt1 395 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 617-4 651 ntGCF_002891615::NZ_LJCI01000028.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002891615::NZ_LJCI01000028.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LJCI01000028.1All displayed genes belong to this local TCS context.
Neighborhood span2 617-4 651 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 617 nt4 651 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1785887Run 6 · HK · 6 sequences
Representative sequenceGCF_002301165#BGU11_RS16850Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1785887

Simplified PFAM architecture for HKOC_1785887

PFAM domain coverage: 145 / 464 aa (31.3%)

1 aa464 aa
HisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 2
  • Matched identifier: HKOC_1785887
  • Positioned domains: HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_002301165#BGU11_RS16850

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002891615
AssemblyASM289161v1 · Scaffoldhaploid
Genome composition4 208 917 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key