Gene detail

AMR93_RS14005

Histidine kinase, Classic

Clostridioides difficile · GCF_002891495

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002891495#AMR93_RS14005Stable P2CS identifier used across views.
GenomeGCF_002891495Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1505324Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_169462977.1 · MIST4 AMR93_RS14005RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000646:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:4.24e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:2.82e-27:495:106:109
  • Raw architecture: HAMP:212:0.00000646:279:68:69#HisKA:289:4.24e-17:347:59:64#HATPase_c:395:2.82e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002891495::NZ_LJCJ01000010.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2251-4444Genomic interval covered by the local TCS group.
Context group IDGCF_002891495::NZ_LJCJ01000010.1::G00008
Context members
AMR93_RS14005AMR93_RS14010
Partner locus tags
AMR93_RS14005AMR93_RS14010
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_169462977.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAMR93_RS14005Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_LJCJ01000010.1Sequence record reported by the local genomic context database.
Genomic interval2 251-3 738 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 251-4 444 ntGCF_002891495::NZ_LJCJ01000010.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002891495::NZ_LJCJ01000010.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LJCJ01000010.1All displayed genes belong to this local TCS context.
Neighborhood span2 251-4 444 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 251 nt4 444 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1505324Run 6 · HK · 5 sequences
Representative sequenceGCF_002891495#AMR93_RS14005The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1505324

Simplified PFAM architecture for HKOC_1505324

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1505324
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_002891495#AMR93_RS14005

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002891495
AssemblyASM289149v1 · Contighaploid
Genome composition4 282 787 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key