Gene detail

CDL19_RS06655

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865465

ClassHKTypeClassicLength572 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865465#CDL19_RS06655Stable P2CS identifier used across views.
GenomeGCF_002865465Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1202197Run 6 · 87 sequences · id 100% · cov 80%
External referencesWP_009244016.1 · A0A829NNJ7 · MIST4 CDL19_RS06655RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length572 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage459 / 572 aa (80.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa572 aa
dCache_1: 42-245 aa (204 aa)1HAMP: 281-351 aa (71 aa)2His_kinase: 367-446 aa (80 aa)3HATPase_c: 463-566 aa (104 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-245 aa · 204 aa · 35.7% of protein
Raw tokendCache_1:42:0.00000000375:245:208:195
2 HAMP#2
281-351 aa · 71 aa · 12.4% of protein
Raw tokenHAMP:281:0.00000036:351:71:69
3 His_kinase#3
367-446 aa · 80 aa · 14.0% of protein
Raw tokenHis_kinase:367:3.07e-29:446:80:80
4 HATPase_c#4
463-566 aa · 104 aa · 18.2% of protein
Raw tokenHATPase_c:463:0.000000000000937:566:110:109
  • Raw architecture: dCache_1:42:0.00000000375:245:208:195#HAMP:281:0.00000036:351:71:69#His_kinase:367:3.07e-29:446:80:80#HATPase_c:463:0.000000000000937:566:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865465::NZ_NIHP01000008.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span73531-76763Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL19_06645RefSeq proteinWP_009244016.1
Context group IDGCF_002865465::NZ_NIHP01000008.1::G00047
Context members
CDL19_RS06650CDL19_RS06655
Partner locus tags
CDL19_RS06650CDL19_RS06655
Partner old locus tags
CDL19_06640CDL19_06645
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009244016.1Primary protein accession used for annex mappings.
UniProt accessionA0A829NNJ7Primary UniProt accession resolved in the annex database.
UniProt IDA0A829NNJ7_MEDG5Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL19_RS06655Primary locus identifier stored in the genes table.
Old locus tagCDL19_06645Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHP01000008.1Sequence record reported by the local genomic context database.
Genomic interval75 045-76 763 nt1 719 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span73 531-76 763 ntGCF_002865465::NZ_NIHP01000008.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865465::NZ_NIHP01000008.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHP01000008.1All displayed genes belong to this local TCS context.
Neighborhood span73 531-76 763 nt3 233 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
73 531 nt76 763 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL19_RS06650GCF_002865465#CDL19_RS06650
RRunclassified

73 531-75 057 nt · Reverse (-)

Old locus CDL19_06640RefSeq WP_009244015.1
CDL19_RS06655GCF_002865465#CDL19_RS06655
HKClassicCurrent focus

75 045-76 763 nt · Reverse (-)

Old locus CDL19_06645RefSeq WP_009244016.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1202197Run 6 · HK · 87 sequences
Representative sequenceGCF_000169475#RUMGNA_RS06030Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1202197

Simplified PFAM architecture for HKOC_1202197

PFAM domain coverage: 384 / 572 aa (67.1%)

1 aa572 aa
dCache_1: 43-245 aadCache_1His_kinase: 367-446 aaHis_kinaseHATPase_c: 465-565 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[43-245] | His_kinase[367-446] | HATPase_c[465-565]
  • Domain count: 3
  • Matched identifier: HKOC_1202197
  • Positioned domains: dCache_1 43-245 ; His_kinase 367-446 ; HATPase_c 465-565
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS06030

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865465
AssemblyASM286546v1 · Scaffoldhaploid
Genome composition3 421 101 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key