Gene detail

CDL27_RS09560

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865405

ClassHKTypeClassicLength571 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865405#CDL27_RS09560Stable P2CS identifier used across views.
GenomeGCF_002865405Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1208210Run 6 · 7 sequences · id 100% · cov 80% · representative
External referencesWP_064787187.1 · A0AB36DHK2 · MIST4 CDL27_RS09560RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length571 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage430 / 571 aa (75.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa571 aa
dCache_1: 42-221 aa (180 aa)1HAMP: 281-347 aa (67 aa)2His_kinase: 362-441 aa (80 aa)3HATPase_c: 458-560 aa (103 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-221 aa · 180 aa · 31.5% of protein
Raw tokendCache_1:42:0.00000772:221:181:195
2 HAMP#2
281-347 aa · 67 aa · 11.7% of protein
Raw tokenHAMP:281:0.0000000000107:347:67:69
3 His_kinase#3
362-441 aa · 80 aa · 14.0% of protein
Raw tokenHis_kinase:362:2.01e-28:441:80:80
4 HATPase_c#4
458-560 aa · 103 aa · 18.0% of protein
Raw tokenHATPase_c:458:0.000000000000163:560:112:109
  • Raw architecture: dCache_1:42:0.00000772:221:181:195#HAMP:281:0.0000000000107:347:67:69#His_kinase:362:2.01e-28:441:80:80#HATPase_c:458:0.000000000000163:560:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865405::NZ_NIHO01000020.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40220-43445Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL27_09535RefSeq proteinWP_064787187.1
Context group IDGCF_002865405::NZ_NIHO01000020.1::G00014
Context members
CDL27_RS09560CDL27_RS09565
Partner locus tags
CDL27_RS09560CDL27_RS09565
Partner old locus tags
CDL27_09535CDL27_09540
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_064787187.1Primary protein accession used for annex mappings.
UniProt accessionA0AB36DHK2Primary UniProt accession resolved in the annex database.
UniProt IDA0AB36DHK2_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL27_RS09560Primary locus identifier stored in the genes table.
Old locus tagCDL27_09535Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHO01000020.1Sequence record reported by the local genomic context database.
Genomic interval40 220-41 935 nt1 716 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span40 220-43 445 ntGCF_002865405::NZ_NIHO01000020.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865405::NZ_NIHO01000020.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHO01000020.1All displayed genes belong to this local TCS context.
Neighborhood span40 220-43 445 nt3 226 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 220 nt43 445 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL27_RS09560GCF_002865405#CDL27_RS09560
HKClassicCurrent focus

40 220-41 935 nt · Reverse (-)

Old locus CDL27_09535RefSeq WP_064787187.1
CDL27_RS09565GCF_002865405#CDL27_RS09565
RRunclassified

41 907-43 445 nt · Reverse (-)

Old locus CDL27_09540RefSeq WP_022037123.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1208210Run 6 · HK · 7 sequences
Representative sequenceGCF_002865405#CDL27_RS09560The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1208210

Simplified PFAM architecture for HKOC_1208210

PFAM domain coverage: 230 / 571 aa (40.3%)

1 aa571 aa
HAMP: 295-346 aaHAMPHis_kinase: 363-439 aaHis_kinaseHATPase_c: 459-559 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[295-346] | His_kinase[363-439] | HATPase_c[459-559]
  • Domain count: 3
  • Matched identifier: HKOC_1208210
  • Positioned domains: HAMP 295-346 ; His_kinase 363-439 ; HATPase_c 459-559
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865405#CDL27_RS09560

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865405
AssemblyASM286540v1 · Scaffoldhaploid
Genome composition3 440 746 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 79 · HK 39 · RR 40CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key