Gene detail

CDL21_RS13990

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865385

ClassHKTypeClassicLength572 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865385#CDL21_RS13990Stable P2CS identifier used across views.
GenomeGCF_002865385Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1203118Run 6 · 11 sequences · id 100% · cov 80%
External referencesWP_242953186.1 · A0A9Q4EXU8 · MIST4 CDL21_RS13990RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length572 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage459 / 572 aa (80.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa572 aa
dCache_1: 42-245 aa (204 aa)1HAMP: 281-351 aa (71 aa)2His_kinase: 367-446 aa (80 aa)3HATPase_c: 463-566 aa (104 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-245 aa · 204 aa · 35.7% of protein
Raw tokendCache_1:42:0.0000000282:245:208:195
2 HAMP#2
281-351 aa · 71 aa · 12.4% of protein
Raw tokenHAMP:281:0.000000342:351:71:69
3 His_kinase#3
367-446 aa · 80 aa · 14.0% of protein
Raw tokenHis_kinase:367:2.86e-29:446:80:80
4 HATPase_c#4
463-566 aa · 104 aa · 18.2% of protein
Raw tokenHATPase_c:463:0.00000000000114:566:110:109
  • Raw architecture: dCache_1:42:0.0000000282:245:208:195#HAMP:281:0.000000342:351:71:69#His_kinase:367:2.86e-29:446:80:80#HATPase_c:463:0.00000000000114:566:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865385::NZ_NIHV01000025.1::G00024
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span10783-14015Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL21_13975RefSeq proteinWP_242953186.1
Context group IDGCF_002865385::NZ_NIHV01000025.1::G00024
Context members
CDL21_RS13985CDL21_RS13990
Partner locus tags
CDL21_RS13985CDL21_RS13990
Partner old locus tags
CDL21_13970CDL21_13975
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_242953186.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q4EXU8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q4EXU8_MEDGNDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL21_RS13990Primary locus identifier stored in the genes table.
Old locus tagCDL21_13975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHV01000025.1Sequence record reported by the local genomic context database.
Genomic interval12 297-14 015 nt1 719 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span10 783-14 015 ntGCF_002865385::NZ_NIHV01000025.1::G00024

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865385::NZ_NIHV01000025.1::G00024

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHV01000025.1All displayed genes belong to this local TCS context.
Neighborhood span10 783-14 015 nt3 233 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 783 nt14 015 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL21_RS13985GCF_002865385#CDL21_RS13985
RRunclassified

10 783-12 309 nt · Reverse (-)

Old locus CDL21_13970RefSeq WP_022038171.1
CDL21_RS13990GCF_002865385#CDL21_RS13990
HKClassicCurrent focus

12 297-14 015 nt · Reverse (-)

Old locus CDL21_13975RefSeq WP_242953186.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1203118Run 6 · HK · 11 sequences
Representative sequenceGCF_002865305#CDL24_RS14075Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1203118

Simplified PFAM architecture for HKOC_1203118

PFAM domain coverage: 181 / 572 aa (31.6%)

1 aa572 aa
His_kinase: 367-446 aaHis_kinaseHATPase_c: 465-565 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[367-446] | HATPase_c[465-565]
  • Domain count: 2
  • Matched identifier: HKOC_1203118
  • Positioned domains: His_kinase 367-446 ; HATPase_c 465-565
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865305#CDL24_RS14075

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865385
AssemblyASM286538v1 · Scaffoldhaploid
Genome composition3 060 122 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 84 · HK 40 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key