Gene detail

CDL25_RS10975

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865355

ClassHKTypeClassicLength494 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865355#CDL25_RS10975Stable P2CS identifier used across views.
GenomeGCF_002865355Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1509581Run 6 · 131 sequences · id 100% · cov 80%
External referencesWP_004841387.1 · A7B061 · MIST4 CDL25_RS10975RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length494 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 494 aa (50.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa494 aa
HAMP: 167-236 aa (70 aa)1HisKA: 261-328 aa (68 aa)2HATPase_c: 373-481 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
167-236 aa · 70 aa · 14.2% of protein
Raw tokenHAMP:167:1.25e-16:236:70:69
2 HisKA#2
261-328 aa · 68 aa · 13.8% of protein
Raw tokenHisKA:261:0.0000000000000308:328:68:64
3 HATPase_c#3
373-481 aa · 109 aa · 22.1% of protein
Raw tokenHATPase_c:373:2.51e-18:481:110:109
  • Raw architecture: HAMP:167:1.25e-16:236:70:69#HisKA:261:0.0000000000000308:328:68:64#HATPase_c:373:2.51e-18:481:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865355::NZ_NIHR01000020.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16220-18381Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL25_10955RefSeq proteinWP_004841387.1
Context group IDGCF_002865355::NZ_NIHR01000020.1::G00019
Context members
CDL25_RS10970CDL25_RS10975
Partner locus tags
CDL25_RS10970CDL25_RS10975
Partner old locus tags
CDL25_10950CDL25_10955
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004841387.1Primary protein accession used for annex mappings.
UniProt accessionA7B061Primary UniProt accession resolved in the annex database.
UniProt IDA7B061_MEDG7Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL25_RS10975Primary locus identifier stored in the genes table.
Old locus tagCDL25_10955Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHR01000020.1Sequence record reported by the local genomic context database.
Genomic interval16 897-18 381 nt1 485 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span16 220-18 381 ntGCF_002865355::NZ_NIHR01000020.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865355::NZ_NIHR01000020.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHR01000020.1All displayed genes belong to this local TCS context.
Neighborhood span16 220-18 381 nt2 162 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 220 nt18 381 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL25_RS10970GCF_002865355#CDL25_RS10970
RROmpR

16 220-16 897 nt · Forward (+)

Old locus CDL25_10950RefSeq WP_009245046.1
CDL25_RS10975GCF_002865355#CDL25_RS10975
HKClassicCurrent focus

16 897-18 381 nt · Forward (+)

Old locus CDL25_10955RefSeq WP_004841387.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1509581Run 6 · HK · 131 sequences
Representative sequenceGCF_000169475#RUMGNA_RS04090Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1509581

Simplified PFAM architecture for HKOC_1509581

PFAM domain coverage: 226 / 494 aa (45.7%)

1 aa494 aa
HAMP: 184-235 aaHAMPHisKA: 261-326 aaHisKAHATPase_c: 374-481 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[184-235] | HisKA[261-326] | HATPase_c[374-481]
  • Domain count: 3
  • Matched identifier: HKOC_1509581
  • Positioned domains: HAMP 184-235 ; HisKA 261-326 ; HATPase_c 374-481
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS04090

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865355
AssemblyASM286535v1 · Scaffoldhaploid
Genome composition3 415 781 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key