1 HAMP#1
288-357 aa · 70 aa · 12.0% of protein
Raw token
HAMP:288:0.00000000212:357:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDL25_RS10485
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_002865355
ClassHKTypeClassicLength583 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865355#CDL25_RS10485Stable P2CS identifier used across views.
GenomeGCF_002865355Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length583 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 583 aa (43.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa583 aa
Domain-by-domain annotation3 items
2 His_kinase#2
372-452 aa · 81 aa · 13.9% of protein
Raw token
His_kinase:372:3.78e-22:452:81:803 HATPase_c#3
475-575 aa · 101 aa · 17.3% of protein
Raw token
HATPase_c:475:0.000000000000116:575:105:109- Raw architecture: HAMP:288:0.00000000212:357:70:69#His_kinase:372:3.78e-22:452:81:80#HATPase_c:475:0.000000000000116:575:105:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002865355::NZ_NIHR01000018.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span48717-51526Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL25_10475RefSeq proteinWP_004844762.1
Context group ID
GCF_002865355::NZ_NIHR01000018.1::G00016Context members
CDL25_RS10485CDL25_RS10490
Partner locus tags
CDL25_RS10485CDL25_RS10490
Partner old locus tags
CDL25_10475CDL25_10480
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004844762.1Primary protein accession used for annex mappings.
UniProt accessionA7B8B0Primary UniProt accession resolved in the annex database.
UniProt IDA7B8B0_MEDG7Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDL25_RS10485Primary locus identifier stored in the genes table.
Old locus tagCDL25_10475Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHR01000018.1Sequence record reported by the local genomic context database.
Genomic interval48 717-50 468 nt1 752 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span48 717-51 526 ntGCF_002865355::NZ_NIHR01000018.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002865355::NZ_NIHR01000018.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHR01000018.1All displayed genes belong to this local TCS context.
Neighborhood span48 717-51 526 nt2 810 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
48 717 nt51 526 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDL25_RS10485GCF_002865355#CDL25_RS10485
HKClassicCurrent focus
48 717-50 468 nt · Forward (+)
CDL25_RS10490GCF_002865355#CDL25_RS10490
RRunclassified
50 456-51 526 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000169475#RUMGNA_RS16720Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1147261
Simplified PFAM architecture for HKOC_1147261
PFAM domain coverage: 183 / 583 aa (31.4%)
1 aa583 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[372-451] | HATPase_c[472-574]
- Domain count: 2
- Matched identifier: HKOC_1147261
- Positioned domains: His_kinase 372-451 ; HATPase_c 472-574
Cluster members and taxonomy
Representative gene: GCF_000169475#RUMGNA_RS16720
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865355
AssemblyASM286535v1 · Scaffoldhaploid
Genome composition3 415 781 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key