Gene detail

CDL25_RS00095

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865355

ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865355#CDL25_RS00095Stable P2CS identifier used across views.
GenomeGCF_002865355Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1874327Run 6 · 100 sequences · id 100% · cov 80%
External referencesWP_009243777.1 · A0A829NW67 · MIST4 CDL25_RS00095RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 457 aa (52.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
HAMP: 144-213 aa (70 aa)1HisKA: 238-302 aa (65 aa)2HATPase_c: 348-451 aa (104 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-213 aa · 70 aa · 15.3% of protein
Raw tokenHAMP:144:0.0000000000198:213:70:69
2 HisKA#2
238-302 aa · 65 aa · 14.2% of protein
Raw tokenHisKA:238:0.000000000148:302:65:64
3 HATPase_c#3
348-451 aa · 104 aa · 22.8% of protein
Raw tokenHATPase_c:348:3.32e-18:451:109:109
  • Raw architecture: HAMP:144:0.0000000000198:213:70:69#HisKA:238:0.000000000148:302:65:64#HATPase_c:348:3.32e-18:451:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865355::NZ_NIHR01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16691-18719Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL25_00095RefSeq proteinWP_009243777.1
Context group IDGCF_002865355::NZ_NIHR01000001.1::G00001
Context members
CDL25_RS00095CDL25_RS00100
Partner locus tags
CDL25_RS00095CDL25_RS00100
Partner old locus tags
CDL25_00095CDL25_00100
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009243777.1Primary protein accession used for annex mappings.
UniProt accessionA0A829NW67Primary UniProt accession resolved in the annex database.
UniProt IDA0A829NW67_MEDG5Display identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL25_RS00095Primary locus identifier stored in the genes table.
Old locus tagCDL25_00095Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHR01000001.1Sequence record reported by the local genomic context database.
Genomic interval16 691-18 064 nt1 374 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span16 691-18 719 ntGCF_002865355::NZ_NIHR01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865355::NZ_NIHR01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHR01000001.1All displayed genes belong to this local TCS context.
Neighborhood span16 691-18 719 nt2 029 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 691 nt18 719 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL25_RS00095GCF_002865355#CDL25_RS00095
HKClassicCurrent focus

16 691-18 064 nt · Reverse (-)

Old locus CDL25_00095RefSeq WP_009243777.1
CDL25_RS00100GCF_002865355#CDL25_RS00100
RROmpR

18 048-18 719 nt · Reverse (-)

Old locus CDL25_00100RefSeq WP_009243778.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1874327Run 6 · HK · 100 sequences
Representative sequenceGCF_000507805#HMPREF1201_RS02010Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1874327

Simplified PFAM architecture for HKOC_1874327

PFAM domain coverage: 216 / 457 aa (47.3%)

1 aa457 aa
HAMP: 163-212 aaHAMPHisKA: 239-302 aaHisKAHATPase_c: 349-450 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[163-212] | HisKA[239-302] | HATPase_c[349-450]
  • Domain count: 3
  • Matched identifier: HKOC_1874327
  • Positioned domains: HAMP 163-212 ; HisKA 239-302 ; HATPase_c 349-450
Cluster members and taxonomy
Visualization

Representative gene: GCF_000507805#HMPREF1201_RS02010

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865355
AssemblyASM286535v1 · Scaffoldhaploid
Genome composition3 415 781 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key