Gene detail

CDL23_RS02060

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865345

ClassHKTypeClassicLength569 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865345#CDL23_RS02060Stable P2CS identifier used across views.
GenomeGCF_002865345Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1217362Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_101883736.1 · A0A2N5PQG0 · MIST4 CDL23_RS02060RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length569 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage464 / 569 aa (81.5%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa569 aa
dCache_1: 48-264 aa (217 aa)1HAMP: 283-348 aa (66 aa)2His_kinase: 369-446 aa (78 aa)3HATPase_c: 462-564 aa (103 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
48-264 aa · 217 aa · 38.1% of protein
Raw tokendCache_1:48:0.0000000000000536:264:228:195
2 HAMP#2
283-348 aa · 66 aa · 11.6% of protein
Raw tokenHAMP:283:0.000000726:348:66:69
3 His_kinase#3
369-446 aa · 78 aa · 13.7% of protein
Raw tokenHis_kinase:369:2.17e-26:446:78:80
4 HATPase_c#4
462-564 aa · 103 aa · 18.1% of protein
Raw tokenHATPase_c:462:0.00000000328:564:117:109
  • Raw architecture: dCache_1:48:0.0000000000000536:264:228:195#HAMP:283:0.000000726:348:66:69#His_kinase:369:2.17e-26:446:78:80#HATPase_c:462:0.00000000328:564:117:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865345::NZ_NIHT01000002.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span131994-135199Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL23_02055RefSeq proteinWP_101883736.1
Context group IDGCF_002865345::NZ_NIHT01000002.1::G00016
Context members
CDL23_RS02055CDL23_RS02060
Partner locus tags
CDL23_RS02055CDL23_RS02060
Partner old locus tags
CDL23_02050CDL23_02055
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_101883736.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5PQG0Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5PQG0_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL23_RS02060Primary locus identifier stored in the genes table.
Old locus tagCDL23_02055Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHT01000002.1Sequence record reported by the local genomic context database.
Genomic interval133 490-135 199 nt1 710 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span131 994-135 199 ntGCF_002865345::NZ_NIHT01000002.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865345::NZ_NIHT01000002.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHT01000002.1All displayed genes belong to this local TCS context.
Neighborhood span131 994-135 199 nt3 206 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
131 994 nt135 199 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL23_RS02055GCF_002865345#CDL23_RS02055
RRunclassified

131 994-133 499 nt · Reverse (-)

Old locus CDL23_02050RefSeq WP_101883735.1
CDL23_RS02060GCF_002865345#CDL23_RS02060
HKClassicCurrent focus

133 490-135 199 nt · Reverse (-)

Old locus CDL23_02055RefSeq WP_101883736.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1217362Run 6 · HK · 1 sequences
Representative sequenceGCF_002865345#CDL23_RS02060The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1217362

Simplified PFAM architecture for HKOC_1217362

PFAM domain coverage: 177 / 569 aa (31.1%)

1 aa569 aa
His_kinase: 369-445 aaHis_kinaseHATPase_c: 464-563 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[369-445] | HATPase_c[464-563]
  • Domain count: 2
  • Matched identifier: HKOC_1217362
  • Positioned domains: His_kinase 369-445 ; HATPase_c 464-563
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865345#CDL23_RS02060

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865345
AssemblyASM286534v1 · Scaffoldhaploid
Genome composition3 271 201 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 81 · HK 38 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key