Gene detail

CDL24_RS05560

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865305

ClassHKTypeClassicLength602 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865305#CDL24_RS05560Stable P2CS identifier used across views.
GenomeGCF_002865305Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1043063Run 6 · 10 sequences · id 100% · cov 80% · representative
External referencesWP_101874808.1 · A0A9Q4I3D7 · MIST4 CDL24_RS05560RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length602 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage264 / 602 aa (43.9%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa602 aa
HAMP: 301-382 aa (82 aa)1His_kinase: 397-476 aa (80 aa)2HATPase_c: 496-597 aa (102 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
301-382 aa · 82 aa · 13.6% of protein
Raw tokenHAMP:301:0.000000000313:382:82:69
2 His_kinase#2
397-476 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:397:3.54e-22:476:80:80
3 HATPase_c#3
496-597 aa · 102 aa · 16.9% of protein
Raw tokenHATPase_c:496:0.0000000000143:597:104:109
  • Raw architecture: HAMP:301:0.000000000313:382:82:69#His_kinase:397:3.54e-22:476:80:80#HATPase_c:496:0.0000000000143:597:104:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865305::NZ_NIHU01000007.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span39935-43389Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL24_05555RefSeq proteinWP_101874808.1
Context group IDGCF_002865305::NZ_NIHU01000007.1::G00036
Context members
CDL24_RS05560CDL24_RS05565
Partner locus tags
CDL24_RS05560CDL24_RS05565
Partner old locus tags
CDL24_05555CDL24_05560
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_101874808.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q4I3D7Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q4I3D7_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL24_RS05560Primary locus identifier stored in the genes table.
Old locus tagCDL24_05555Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHU01000007.1Sequence record reported by the local genomic context database.
Genomic interval39 935-41 743 nt1 809 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span39 935-43 389 ntGCF_002865305::NZ_NIHU01000007.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865305::NZ_NIHU01000007.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHU01000007.1All displayed genes belong to this local TCS context.
Neighborhood span39 935-43 389 nt3 455 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
39 935 nt43 389 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL24_RS05560GCF_002865305#CDL24_RS05560
HKClassicCurrent focus

39 935-41 743 nt · Forward (+)

Old locus CDL24_05555RefSeq WP_101874808.1
CDL24_RS05565GCF_002865305#CDL24_RS05565
RRunclassified

41 779-43 389 nt · Forward (+)

Old locus CDL24_05560RefSeq WP_101874807.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1043063Run 6 · HK · 10 sequences
Representative sequenceGCF_002865305#CDL24_RS05560The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1043063

Simplified PFAM architecture for HKOC_1043063

PFAM domain coverage: 179 / 602 aa (29.7%)

1 aa602 aa
His_kinase: 398-474 aaHis_kinaseHATPase_c: 496-597 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[398-474] | HATPase_c[496-597]
  • Domain count: 2
  • Matched identifier: HKOC_1043063
  • Positioned domains: His_kinase 398-474 ; HATPase_c 496-597
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865305#CDL24_RS05560

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865305
AssemblyASM286530v1 · Scaffoldhaploid
Genome composition3 078 886 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 80 · HK 38 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key