Gene detail

NRBB02_RS04060

Histidine kinase, Classic

Bifidobacterium breve · GCF_002838265

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_002838265#NRBB02_RS04060Stable P2CS identifier used across views.
GenomeGCF_002838265Bacteria; Bacillati; Actinomycetota; Actinomycetes; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium
Selected clusterHKOC_1504342Run 6 · 53 sequences · id 100% · cov 80%
External referencesWP_014483900.1 · MIST4 NRBB02_RS04060RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NPAS_4HisKA_2HATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage414 / 495 aa (83.6%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 PAS_4,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
H_kinase_N: 9-145 aa (137 aa)1PAS_4: 175-278 aa (104 aa)2HisKA_2: 292-361 aa (70 aa)3HATPase_c: 388-490 aa (103 aa)4
Domain-by-domain annotation4 items
1 H_kinase_N#1
9-145 aa · 137 aa · 27.7% of protein
Raw tokenH_kinase_N:9:1.96e-50:145:138:139
2 PAS_4#2
175-278 aa · 104 aa · 21.0% of protein
Raw tokenPAS_4:175:0.00000000402:278:109:110
3 HisKA_2#3
292-361 aa · 70 aa · 14.1% of protein
Raw tokenHisKA_2:292:1.35e-30:361:71:76
4 HATPase_c#4
388-490 aa · 103 aa · 20.8% of protein
Raw tokenHATPase_c:388:0.00000000000000151:490:112:109
  • Raw architecture: H_kinase_N:9:1.96e-50:145:138:139#PAS_4:175:0.00000000402:278:109:110#HisKA_2:292:1.35e-30:361:71:76#HATPase_c:388:0.00000000000000151:490:112:109
  • Domain description: 1 H_kinase_N,1 PAS_4,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_002838265::NZ_CP021385.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span929574-931061Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNRBB02_0769RefSeq proteinWP_014483900.1
Context group IDGCF_002838265::NZ_CP021385.1::G00003
Context members
NRBB02_RS04060
Partner locus tags
NRBB02_RS04060
Partner old locus tags
NRBB02_0769
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_014483900.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNRBB02_RS04060Primary locus identifier stored in the genes table.
Old locus tagNRBB02_0769Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP021385.1Sequence record reported by the local genomic context database.
Genomic interval929 574-931 061 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span929 574-931 061 ntGCF_002838265::NZ_CP021385.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002838265::NZ_CP021385.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP021385.1All displayed genes belong to this local TCS context.
Neighborhood span929 574-931 061 nt1 488 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
929 574 nt931 061 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NRBB02_RS04060GCF_002838265#NRBB02_RS04060
HKClassicCurrent focus

929 574-931 061 nt · Forward (+)

Old locus NRBB02_0769RefSeq WP_014483900.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504342Run 6 · HK · 53 sequences
Representative sequenceGCF_000213865#HMPREF9228_RS05440Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + PAS_4 + HisKA_2 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504342

Simplified PFAM architecture for HKOC_1504342

PFAM domain coverage: 416 / 495 aa (84.0%)

1 aa495 aa
GAF_PdtaS: 5-141 aaGAF_PdtaSPAS_4: 174-278 aaPAS_4HisKA_2: 292-363 aaHisKA_2HATPase_c: 388-489 aaHATPase_c
GAF_PdtaSPAS_4HisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + PAS_4 + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[5-141] | PAS_4[174-278] | HisKA_2[292-363] | HATPase_c[388-489]
  • Domain count: 4
  • Matched identifier: HKOC_1504342
  • Positioned domains: GAF_PdtaS 5-141 ; PAS_4 174-278 ; HisKA_2 292-363 ; HATPase_c 388-489
Cluster members and taxonomy
Visualization

Representative gene: GCF_000213865#HMPREF9228_RS05440

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 685 · GCF_002838265
AssemblyASM283826v1 · Complete Genomehaploid
Genome composition2 289 884 bp · 58,5% GCBifidobacterium breve
Signal transduction countsGenes 25 · HK 10 · RR 14CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumActinomycetotaClassActinomycetesOrderBifidobacterialesFamilyBifidobacteriaceaeGenusBifidobacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Actinomycetota4Actinomycetes5Bifidobacteriales6Bifidobacteriaceae7Bifidobacterium

Related genes

Preview from the same derived genome key