1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw token
HisKA:218:0.0000000000698:278:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CWR55_RS12745
Histidine kinase, Classic
Clostridioides difficile · GCF_002812625
ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002812625#CWR55_RS12745Stable P2CS identifier used across views.
GenomeGCF_002812625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa436 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw token
HATPase_c:334:5.93e-25:433:100:109- Raw architecture: HisKA:218:0.0000000000698:278:61:64#HATPase_c:334:5.93e-25:433:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002812625::NZ_CP025046.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2681434-2683445Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCWR55_12745RefSeq proteinWP_004454840.1
Context group ID
GCF_002812625::NZ_CP025046.1::G00040Context members
CWR55_RS12745CWR55_RS12750
Partner locus tags
CWR55_RS12745CWR55_RS12750
Partner old locus tags
CWR55_12745CWR55_12750
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004454840.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q7WRG2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q7WRG2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCWR55_RS12745Primary locus identifier stored in the genes table.
Old locus tagCWR55_12745Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP025046.1Sequence record reported by the local genomic context database.
Genomic interval2 681 434-2 682 744 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 681 434-2 683 445 ntGCF_002812625::NZ_CP025046.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002812625::NZ_CP025046.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP025046.1All displayed genes belong to this local TCS context.
Neighborhood span2 681 434-2 683 445 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 681 434 nt2 683 445 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CWR55_RS12745GCF_002812625#CWR55_RS12745
HKClassicCurrent focus
2 681 434-2 682 744 nt · Reverse (-)
CWR55_RS12750GCF_002812625#CWR55_RS12750
RROmpR
2 682 738-2 683 445 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000154625#QAB_RS0215090Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2113131
Simplified PFAM architecture for HKOC_2113131
PFAM domain coverage: 166 / 436 aa (38.1%)
1 aa436 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[217-278] | HATPase_c[330-433]
- Domain count: 2
- Matched identifier: HKOC_2113131
- Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Representative gene: GCF_000154625#QAB_RS0215090
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002812625
AssemblyASM281262v1 · Complete Genomehaploid
Genome composition4 188 456 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 46 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key