1 Response_reg#1
5-117 aa · 113 aa · 48.7% of protein
Raw token
Response_reg:5:2.17e-22:117:113:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CWR57_RS14315
Response regulator, unclassified
Clostridioides difficile · GCF_002812585
ClassRRTypeunclassifiedLength232 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002812585#CWR57_RS14315Stable P2CS identifier used across views.
GenomeGCF_002812585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regHTH_AraC
Protein length232 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage154 / 232 aa (66.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa232 aa
Domain-by-domain annotation2 items
2 HTH_AraC#2
186-226 aa · 41 aa · 17.7% of protein
Raw token
HTH_AraC:186:0.0000383:226:41:42- Raw architecture: Response_reg:5:2.17e-22:117:113:111#HTH_AraC:186:0.0000383:226:41:42
- Domain description: 1 Response_reg,1 HTH_AraC
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002812585::NZ_CP025044.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3076783-3079100Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCWR57_14315RefSeq proteinWP_003436119.1
Context group ID
GCF_002812585::NZ_CP025044.1::G00046Context members
CWR57_RS14315CWR57_RS14320
Partner locus tags
CWR57_RS14315CWR57_RS14320
Partner old locus tags
CWR57_14315CWR57_14320
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003436119.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NA51Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NA51_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCWR57_RS14315Primary locus identifier stored in the genes table.
Old locus tagCWR57_14315Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP025044.1Sequence record reported by the local genomic context database.
Genomic interval3 076 783-3 077 481 nt699 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 076 783-3 079 100 ntGCF_002812585::NZ_CP025044.1::G00046
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002812585::NZ_CP025044.1::G00046Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP025044.1All displayed genes belong to this local TCS context.
Neighborhood span3 076 783-3 079 100 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 076 783 nt3 079 100 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CWR57_RS14315GCF_002812585#CWR57_RS14315
RRunclassifiedCurrent focus
3 076 783-3 077 481 nt · Reverse (-)
CWR57_RS14320GCF_002812585#CWR57_RS14320
HKClassic
3 077 595-3 079 100 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_012276945#GSQ50_RS11900Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HTH_182 domains in the representative PFAM annotation.
PFAM architecture for RROC_1059373
Simplified PFAM architecture for RROC_1059373
PFAM domain coverage: 189 / 234 aa (80.8%)
1 aa234 aa
Response_regHTH_18
- Simplified architecture: Response_reg + HTH_18
- Raw architecture: Response_reg[5-116] | HTH_18[151-227]
- Domain count: 2
- Matched identifier: RROC_1059373
- Positioned domains: Response_reg 5-116 ; HTH_18 151-227
Cluster members and taxonomy
Representative gene: GCF_012276945#GSQ50_RS11900
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002812585
AssemblyASM281258v1 · Complete Genomehaploid
Genome composition4 190 038 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key