Gene detail

COJ17_RS08485

Histidine kinase, Classic

Bacillus thuringiensis · GCF_002565435

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002565435#COJ17_RS08485Stable P2CS identifier used across views.
GenomeGCF_002565435Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1105137Run 6 · 300 sequences · id 100% · cov 80%
External referencesWP_000964683.1 · A0A9W3PF42 · MIST4 COJ17_RS08485RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage348 / 591 aa (58.9%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
HAMP: 176-244 aa (69 aa)1PAS: 255-355 aa (101 aa)2HisKA: 364-431 aa (68 aa)3HATPase_c: 478-587 aa (110 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
176-244 aa · 69 aa · 11.7% of protein
Raw tokenHAMP:176:0.000000000000013:244:69:69
2 PAS#2
255-355 aa · 101 aa · 17.1% of protein
Raw tokenPAS:255:0.00000375:355:113:113
3 HisKA#3
364-431 aa · 68 aa · 11.5% of protein
Raw tokenHisKA:364:4.15e-18:431:68:64
4 HATPase_c#4
478-587 aa · 110 aa · 18.6% of protein
Raw tokenHATPase_c:478:4.78e-35:587:110:109
  • Raw architecture: HAMP:176:0.000000000000013:244:69:69#PAS:255:0.00000375:355:113:113#HisKA:364:4.15e-18:431:68:64#HATPase_c:478:4.78e-35:587:110:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002565435::NZ_NUWL01000004.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span333994-336485Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCOJ17_08490RefSeq proteinWP_000964683.1
Context group IDGCF_002565435::NZ_NUWL01000004.1::G00052
Context members
COJ17_RS08485COJ17_RS08490
Partner locus tags
COJ17_RS08485COJ17_RS08490
Partner old locus tags
COJ17_08490COJ17_08495
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000964683.1Primary protein accession used for annex mappings.
UniProt accessionA0A9W3PF42Primary UniProt accession resolved in the annex database.
UniProt IDA0A9W3PF42_BACTUDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCOJ17_RS08485Primary locus identifier stored in the genes table.
Old locus tagCOJ17_08490Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NUWL01000004.1Sequence record reported by the local genomic context database.
Genomic interval333 994-335 769 nt1 776 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span333 994-336 485 ntGCF_002565435::NZ_NUWL01000004.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002565435::NZ_NUWL01000004.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NUWL01000004.1All displayed genes belong to this local TCS context.
Neighborhood span333 994-336 485 nt2 492 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
333 994 nt336 485 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

COJ17_RS08485GCF_002565435#COJ17_RS08485
HKClassicCurrent focus

333 994-335 769 nt · Reverse (-)

Old locus COJ17_08490RefSeq WP_000964683.1
COJ17_RS08490GCF_002565435#COJ17_RS08490
RROmpR

335 769-336 485 nt · Reverse (-)

Old locus COJ17_08495RefSeq WP_000426861.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1105137Run 6 · HK · 300 sequences
Representative sequenceGCF_000161495#BTHUR0002_RS07150Use this link to inspect the representative gene detail.
PFAM architectureHisK_sensor + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1105137

Simplified PFAM architecture for HKOC_1105137

PFAM domain coverage: 357 / 591 aa (60.4%)

1 aa591 aa
HisK_sensor: 38-163 aaHisK_sensorHAMP: 193-244 aaHAMPHisKA: 364-431 aaHisKAHATPase_c: 478-588 aaHATPase_c
HisK_sensorHAMPHisKAHATPase_c
  • Simplified architecture: HisK_sensor + HAMP + HisKA + HATPase_c
  • Raw architecture: HisK_sensor[38-163] | HAMP[193-244] | HisKA[364-431] | HATPase_c[478-588]
  • Domain count: 4
  • Matched identifier: HKOC_1105137
  • Positioned domains: HisK_sensor 38-163 ; HAMP 193-244 ; HisKA 364-431 ; HATPase_c 478-588
Cluster members and taxonomy
Visualization

Representative gene: GCF_000161495#BTHUR0002_RS07150

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 428 · GCF_002565435
AssemblyASM256543v1 · Scaffoldhaploid
Genome composition5 691 959 bp · 35,0% GCBacillus thuringiensis
Signal transduction countsGenes 113 · HK 61 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key