1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw token
HisKA:168:0.000000000000401:234:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
V438_RS10585
Histidine kinase, Classic
Clostridioides difficile · GCF_002412385
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002412385#V438_RS10585Stable P2CS identifier used across views.
GenomeGCF_002412385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw token
HATPase_c:280:4.98e-26:388:110:109- Raw architecture: HisKA:168:0.000000000000401:234:67:64#HATPase_c:280:4.98e-26:388:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002412385::NZ_JBOQ01000056.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9684-11547Genomic interval covered by the local TCS group.
Identifiers
Old locus tagV438_10360RefSeq proteinWP_003422313.1
Context group ID
GCF_002412385::NZ_JBOQ01000056.1::G00032Context members
V438_RS10585V438_RS10590
Partner locus tags
V438_RS10585V438_RS10590
Partner old locus tags
V438_10360V438_10365
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003422313.1Primary protein accession used for annex mappings.
UniProt accessionD5Q9X2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q9X2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagV438_RS10585Primary locus identifier stored in the genes table.
Old locus tagV438_10360Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBOQ01000056.1Sequence record reported by the local genomic context database.
Genomic interval9 684-10 865 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 684-11 547 ntGCF_002412385::NZ_JBOQ01000056.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002412385::NZ_JBOQ01000056.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBOQ01000056.1All displayed genes belong to this local TCS context.
Neighborhood span9 684-11 547 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 684 nt11 547 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
V438_RS10585GCF_002412385#V438_RS10585
HKClassicCurrent focus
9 684-10 865 nt · Reverse (-)
V438_RS10590GCF_002412385#V438_RS10590
RROmpR
10 855-11 547 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0217715Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503304
Simplified PFAM architecture for HKOC_2503304
PFAM domain coverage: 175 / 393 aa (44.5%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[168-233] | HATPase_c[281-389]
- Domain count: 2
- Matched identifier: HKOC_2503304
- Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0217715
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002412385
AssemblyK40_5754.1 · Contighaploid
Genome composition3 945 736 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key