Gene detail

V438_RS08985

Histidine kinase, Classic

Clostridioides difficile · GCF_002412385

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002412385#V438_RS08985Stable P2CS identifier used across views.
GenomeGCF_002412385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827783Run 6 · 289 sequences · id 100% · cov 80%
External referencesWP_009905636.1 · A0AAX3GUW7 · MIST4 V438_RS08985RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for V438_RS08985
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.00000103:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:3.27e-25:341:101:109
  • Raw architecture: HisKA:124:0.00000103:189:66:64#HATPase_c:241:3.27e-25:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002412385::NZ_JBOQ01000046.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span146827-148534Genomic interval covered by the local TCS group.
Identifiers
Old locus tagV438_08775RefSeq proteinWP_009905636.1
Context group IDGCF_002412385::NZ_JBOQ01000046.1::G00020
Context members
V438_RS08985V438_RS08990
Partner locus tags
V438_RS08985V438_RS08990
Partner old locus tags
V438_08775V438_08780
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009905636.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3GUW7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3GUW7_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagV438_RS08985Primary locus identifier stored in the genes table.
Old locus tagV438_08775Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBOQ01000046.1Sequence record reported by the local genomic context database.
Genomic interval146 827-147 858 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span146 827-148 534 ntGCF_002412385::NZ_JBOQ01000046.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002412385::NZ_JBOQ01000046.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBOQ01000046.1All displayed genes belong to this local TCS context.
Neighborhood span146 827-148 534 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
146 827 nt148 534 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

V438_RS08985GCF_002412385#V438_RS08985
HKClassicCurrent focus

146 827-147 858 nt · Reverse (-)

Old locus V438_08775RefSeq WP_009905636.1
V438_RS08990GCF_002412385#V438_RS08990
RROmpR

147 848-148 534 nt · Reverse (-)

Old locus V438_08780RefSeq WP_003424116.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827783Run 6 · HK · 289 sequences
Representative sequenceGCF_000155065#QAE_RS0209420Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827783

Simplified PFAM architecture for HKOC_2827783

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827783
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0209420

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002412385
AssemblyK40_5754.1 · Contighaploid
Genome composition3 945 736 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key