1 HAMP#1
127-200 aa · 74 aa · 17.0% of protein
Raw token
HAMP:127:0.00000000417:200:74:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
V438_RS05925
Histidine kinase, Classic
Clostridioides difficile · GCF_002412385
ClassHKTypeClassicLength435 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002412385#V438_RS05925Stable P2CS identifier used across views.
GenomeGCF_002412385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length435 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 435 aa (56.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa435 aa
Domain-by-domain annotation3 items
2 HisKA#2
211-276 aa · 66 aa · 15.2% of protein
Raw token
HisKA:211:0.00000000351:276:66:643 HATPase_c#3
326-432 aa · 107 aa · 24.6% of protein
Raw token
HATPase_c:326:1.85e-25:432:107:109- Raw architecture: HAMP:127:0.00000000417:200:74:69#HisKA:211:0.00000000351:276:66:64#HATPase_c:326:1.85e-25:432:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002412385::NZ_JBOQ01000041.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span10399-12534Genomic interval covered by the local TCS group.
Identifiers
Old locus tagV438_05725RefSeq proteinWP_330360718.1
Context group ID
GCF_002412385::NZ_JBOQ01000041.1::G00010Context members
V438_RS05920V438_RS05925
Partner locus tags
V438_RS05920V438_RS05925
Partner old locus tags
V438_05720V438_05725
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330360718.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagV438_RS05925Primary locus identifier stored in the genes table.
Old locus tagV438_05725Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBOQ01000041.1Sequence record reported by the local genomic context database.
Genomic interval11 227-12 534 nt1 308 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span10 399-12 534 ntGCF_002412385::NZ_JBOQ01000041.1::G00010
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002412385::NZ_JBOQ01000041.1::G00010Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBOQ01000041.1All displayed genes belong to this local TCS context.
Neighborhood span10 399-12 534 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 399 nt12 534 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
V438_RS05920GCF_002412385#V438_RS05920
RROmpR
10 399-11 091 nt · Forward (+)
V438_RS05925GCF_002412385#V438_RS05925
HKClassicCurrent focus
11 227-12 534 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164655#HMPREF0219_RS16665Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2122086
Simplified PFAM architecture for HKOC_2122086
PFAM domain coverage: 222 / 435 aa (51.0%)
1 aa435 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[150-199] | HisKA[212-276] | HATPase_c[326-432]
- Domain count: 3
- Matched identifier: HKOC_2122086
- Positioned domains: HAMP 150-199 ; HisKA 212-276 ; HATPase_c 326-432
Cluster members and taxonomy
Representative gene: GCF_000164655#HMPREF0219_RS16665
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002412385
AssemblyK40_5754.1 · Contighaploid
Genome composition3 945 736 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key