Gene detail

NCKUH21_RS04775

Histidine kinase, Classic

Clostridioides difficile · GCF_002335485

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002335485#NCKUH21_RS04775Stable P2CS identifier used across views.
GenomeGCF_002335485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504245Run 6 · 349 sequences · id 100% · cov 80%
External referencesWP_009888772.1 · A0A0H3N1C9 · MIST4 NCKUH21_RS04775RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for NCKUH21_RS04775
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.0000061:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:3.62e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:2.74e-27:495:106:109
  • Raw architecture: HAMP:212:0.0000061:279:68:69#HisKA:289:3.62e-17:347:59:64#HATPase_c:395:2.74e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002335485::NZ_BDSN01000014.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span52351-54544Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNCKUH21_00943RefSeq proteinWP_009888772.1
Context group IDGCF_002335485::NZ_BDSN01000014.1::G00017
Context members
NCKUH21_RS04770NCKUH21_RS04775
Partner locus tags
NCKUH21_RS04770NCKUH21_RS04775
Partner old locus tags
NCKUH21_00942NCKUH21_00943
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009888772.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N1C9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N1C9_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNCKUH21_RS04775Primary locus identifier stored in the genes table.
Old locus tagNCKUH21_00943Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BDSN01000014.1Sequence record reported by the local genomic context database.
Genomic interval53 057-54 544 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span52 351-54 544 ntGCF_002335485::NZ_BDSN01000014.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002335485::NZ_BDSN01000014.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BDSN01000014.1All displayed genes belong to this local TCS context.
Neighborhood span52 351-54 544 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 351 nt54 544 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NCKUH21_RS04770GCF_002335485#NCKUH21_RS04770
RROmpR

52 351-53 055 nt · Forward (+)

Old locus NCKUH21_00942RefSeq WP_009888771.1
NCKUH21_RS04775GCF_002335485#NCKUH21_RS04775
HKClassicCurrent focus

53 057-54 544 nt · Forward (+)

Old locus NCKUH21_00943RefSeq WP_009888772.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504245Run 6 · HK · 349 sequences
Representative sequenceGCF_000003215#QAC_RS0204900Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504245

Simplified PFAM architecture for HKOC_1504245

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504245
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0204900

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002335485
AssemblyASM233548v1 · Contighaploid
Genome composition4 217 149 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key