Gene detail

BGU72_RS04000

Histidine kinase, Classic

Clostridioides difficile · GCF_002303655

ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303655#BGU72_RS04000Stable P2CS identifier used across views.
GenomeGCF_002303655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1468512Run 6 · 49 sequences · id 100% · cov 80%
External referencesWP_021360920.1 · MIST4 BGU72_RS04000RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
His_kinase: 305-376 aa (72 aa)1HATPase_c: 396-496 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw tokenHis_kinase:305:1e-24:376:72:80
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw tokenHATPase_c:396:0.00000293:496:107:109
  • Raw architecture: His_kinase:305:1e-24:376:72:80#HATPase_c:396:0.00000293:496:107:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303655::NZ_MOTL01000002.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span369868-372185Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU72_03975RefSeq proteinWP_021360920.1
Context group IDGCF_002303655::NZ_MOTL01000002.1::G00008
Context members
BGU72_RS04000BGU72_RS04005
Partner locus tags
BGU72_RS04000BGU72_RS04005
Partner old locus tags
BGU72_03975BGU72_03980
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021360920.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU72_RS04000Primary locus identifier stored in the genes table.
Old locus tagBGU72_03975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOTL01000002.1Sequence record reported by the local genomic context database.
Genomic interval369 868-371 373 nt1 506 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span369 868-372 185 ntGCF_002303655::NZ_MOTL01000002.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303655::NZ_MOTL01000002.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOTL01000002.1All displayed genes belong to this local TCS context.
Neighborhood span369 868-372 185 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
369 868 nt372 185 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU72_RS04000GCF_002303655#BGU72_RS04000
HKClassicCurrent focus

369 868-371 373 nt · Forward (+)

Old locus BGU72_03975RefSeq WP_021360920.1
BGU72_RS04005GCF_002303655#BGU72_RS04005
RRunclassified

371 487-372 185 nt · Forward (+)

Old locus BGU72_03980RefSeq WP_003436119.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1468512Run 6 · HK · 49 sequences
Representative sequenceGCF_000448845#QAQ_RS14130Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1468512

Simplified PFAM architecture for HKOC_1468512

PFAM domain coverage: 137 / 501 aa (27.3%)

1 aa501 aa
Cupin_2: 34-96 aaCupin_2His_kinase: 303-376 aaHis_kinase
Cupin_2His_kinase
  • Simplified architecture: Cupin_2 + His_kinase
  • Raw architecture: Cupin_2[34-96] | His_kinase[303-376]
  • Domain count: 2
  • Matched identifier: HKOC_1468512
  • Positioned domains: Cupin_2 34-96 ; His_kinase 303-376
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448845#QAQ_RS14130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303655
AssemblyASM230365v1 · Contighaploid
Genome composition4 182 475 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 45 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key