Gene detail

BGU65_RS01010

Histidine kinase, Classic

Clostridioides difficile · GCF_002303505

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303505#BGU65_RS01010Stable P2CS identifier used across views.
GenomeGCF_002303505Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504520Run 6 · 103 sequences · id 100% · cov 80%
External referencesWP_021370209.1 · MIST4 BGU65_RS01010RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000636:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:3.41e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:2.81e-27:495:106:109
  • Raw architecture: HAMP:212:0.00000636:279:68:69#HisKA:289:3.41e-17:347:59:64#HATPase_c:395:2.81e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303505::NZ_MOTG01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span223075-225268Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU65_00995RefSeq proteinWP_021370209.1
Context group IDGCF_002303505::NZ_MOTG01000001.1::G00002
Context members
BGU65_RS01005BGU65_RS01010
Partner locus tags
BGU65_RS01005BGU65_RS01010
Partner old locus tags
BGU65_00990BGU65_00995
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021370209.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU65_RS01010Primary locus identifier stored in the genes table.
Old locus tagBGU65_00995Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOTG01000001.1Sequence record reported by the local genomic context database.
Genomic interval223 781-225 268 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span223 075-225 268 ntGCF_002303505::NZ_MOTG01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303505::NZ_MOTG01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOTG01000001.1All displayed genes belong to this local TCS context.
Neighborhood span223 075-225 268 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
223 075 nt225 268 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU65_RS01005GCF_002303505#BGU65_RS01005
RROmpR

223 075-223 779 nt · Forward (+)

Old locus BGU65_00990RefSeq WP_003437036.1
BGU65_RS01010GCF_002303505#BGU65_RS01010
HKClassicCurrent focus

223 781-225 268 nt · Forward (+)

Old locus BGU65_00995RefSeq WP_021370209.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504520Run 6 · HK · 103 sequences
Representative sequenceGCF_000449025#QCG_RS06020Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504520

Simplified PFAM architecture for HKOC_1504520

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504520
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449025#QCG_RS06020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303505
AssemblyASM230350v1 · Contighaploid
Genome composition4 342 698 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 46 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key