Gene detail

BGU60_RS12350

Histidine kinase, Classic

Clostridioides difficile · GCF_002303425

ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303425#BGU60_RS12350Stable P2CS identifier used across views.
GenomeGCF_002303425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2354207Run 6 · 312 sequences · id 100% · cov 80%
External referencesWP_003420373.1 · D5Q708 · MIST4 BGU60_RS12350RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
HisKA: 185-250 aa (66 aa)1HATPase_c: 296-408 aa (113 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw tokenHisKA:185:0.000000000193:250:66:64
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw tokenHATPase_c:296:4.88e-25:408:113:109
  • Raw architecture: HisKA:185:0.000000000193:250:66:64#HATPase_c:296:4.88e-25:408:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303425::NZ_MOTC01000023.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27784-29677Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU60_12155RefSeq proteinWP_003420373.1
Context group IDGCF_002303425::NZ_MOTC01000023.1::G00037
Context members
BGU60_RS12345BGU60_RS12350
Partner locus tags
BGU60_RS12345BGU60_RS12350
Partner old locus tags
BGU60_12150BGU60_12155
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003420373.1Primary protein accession used for annex mappings.
UniProt accessionD5Q708Primary UniProt accession resolved in the annex database.
UniProt IDD5Q708_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU60_RS12350Primary locus identifier stored in the genes table.
Old locus tagBGU60_12155Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOTC01000023.1Sequence record reported by the local genomic context database.
Genomic interval28 445-29 677 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span27 784-29 677 ntGCF_002303425::NZ_MOTC01000023.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303425::NZ_MOTC01000023.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOTC01000023.1All displayed genes belong to this local TCS context.
Neighborhood span27 784-29 677 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 784 nt29 677 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU60_RS12345GCF_002303425#BGU60_RS12345
RROmpR

27 784-28 455 nt · Forward (+)

Old locus BGU60_12150RefSeq WP_003420372.1
BGU60_RS12350GCF_002303425#BGU60_RS12350
HKClassicCurrent focus

28 445-29 677 nt · Forward (+)

Old locus BGU60_12155RefSeq WP_003420373.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2354207Run 6 · HK · 312 sequences
Representative sequenceGCF_000155065#QAE_RS0208365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2354207

Simplified PFAM architecture for HKOC_2354207

PFAM domain coverage: 178 / 410 aa (43.4%)

1 aa410 aa
HisKA: 185-250 aaHisKAHATPase_c: 297-408 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[185-250] | HATPase_c[297-408]
  • Domain count: 2
  • Matched identifier: HKOC_2354207
  • Positioned domains: HisKA 185-250 ; HATPase_c 297-408
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0208365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303425
AssemblyASM230342v1 · Contighaploid
Genome composition4 026 332 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key