Gene detail

BGU60_RS05250

Histidine kinase, Classic

Clostridioides difficile · GCF_002303425

ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303425#BGU60_RS05250Stable P2CS identifier used across views.
GenomeGCF_002303425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2857951Run 6 · 303 sequences · id 100% · cov 80%
External referencesWP_003422275.1 · D5Q9Z1 · MIST4 BGU60_RS05250RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
HisKA: 117-177 aa (61 aa)1HATPase_c: 222-328 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw tokenHisKA:117:0.000000000309:177:61:64
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw tokenHATPase_c:222:2.12e-24:328:108:109
  • Raw architecture: HisKA:117:0.000000000309:177:61:64#HATPase_c:222:2.12e-24:328:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303425::NZ_MOTC01000007.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span116211-117873Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU60_05125RefSeq proteinWP_003422275.1
Context group IDGCF_002303425::NZ_MOTC01000007.1::G00019
Context members
BGU60_RS05245BGU60_RS05250
Partner locus tags
BGU60_RS05245BGU60_RS05250
Partner old locus tags
BGU60_05120BGU60_05125
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003422275.1Primary protein accession used for annex mappings.
UniProt accessionD5Q9Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q9Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU60_RS05250Primary locus identifier stored in the genes table.
Old locus tagBGU60_05125Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOTC01000007.1Sequence record reported by the local genomic context database.
Genomic interval116 884-117 873 nt990 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span116 211-117 873 ntGCF_002303425::NZ_MOTC01000007.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303425::NZ_MOTC01000007.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOTC01000007.1All displayed genes belong to this local TCS context.
Neighborhood span116 211-117 873 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
116 211 nt117 873 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU60_RS05245GCF_002303425#BGU60_RS05245
RROmpR

116 211-116 897 nt · Forward (+)

Old locus BGU60_05120RefSeq WP_003422278.1
BGU60_RS05250GCF_002303425#BGU60_RS05250
HKClassicCurrent focus

116 884-117 873 nt · Forward (+)

Old locus BGU60_05125RefSeq WP_003422275.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2857951Run 6 · HK · 303 sequences
Representative sequenceGCF_000155065#QAE_RS0217625Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2857951

Simplified PFAM architecture for HKOC_2857951

PFAM domain coverage: 169 / 329 aa (51.4%)

1 aa329 aa
HisKA: 116-177 aaHisKAHATPase_c: 222-328 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[116-177] | HATPase_c[222-328]
  • Domain count: 2
  • Matched identifier: HKOC_2857951
  • Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0217625

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303425
AssemblyASM230342v1 · Contighaploid
Genome composition4 026 332 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key