Gene detail

BGU60_RS03385

Histidine kinase, Classic

Clostridioides difficile · GCF_002303425

ClassHKTypeClassicLength376 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303425#BGU60_RS03385Stable P2CS identifier used across views.
GenomeGCF_002303425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2642815Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_095926779.1 · MIST4 BGU60_RS03385RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length376 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 376 aa (65.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa376 aa
HAMP: 62-131 aa (70 aa)1HisKA: 156-221 aa (66 aa)2HATPase_c: 268-376 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
62-131 aa · 70 aa · 18.6% of protein
Raw tokenHAMP:62:0.000000000184:131:70:69
2 HisKA#2
156-221 aa · 66 aa · 17.6% of protein
Raw tokenHisKA:156:0.00000000000000512:221:66:64
3 HATPase_c#3
268-376 aa · 109 aa · 29.0% of protein
Raw tokenHATPase_c:268:6.89e-17:376:110:109
  • Raw architecture: HAMP:62:0.000000000184:131:70:69#HisKA:156:0.00000000000000512:221:66:64#HATPase_c:268:6.89e-17:376:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303425::NZ_MOTC01000005.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span20893-22691Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU60_03275RefSeq proteinWP_095926779.1
Context group IDGCF_002303425::NZ_MOTC01000005.1::G00012
Context members
BGU60_RS03385BGU60_RS03390
Partner locus tags
BGU60_RS03385BGU60_RS03390
Partner old locus tags
BGU60_03275BGU60_03280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_095926779.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU60_RS03385Primary locus identifier stored in the genes table.
Old locus tagBGU60_03275Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOTC01000005.1Sequence record reported by the local genomic context database.
Genomic interval20 893-22 023 nt1 131 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span20 893-22 691 ntGCF_002303425::NZ_MOTC01000005.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303425::NZ_MOTC01000005.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOTC01000005.1All displayed genes belong to this local TCS context.
Neighborhood span20 893-22 691 nt1 799 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
20 893 nt22 691 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU60_RS03385GCF_002303425#BGU60_RS03385
HKClassicCurrent focus

20 893-22 023 nt · Reverse (-)

Old locus BGU60_03275RefSeq WP_095926779.1
BGU60_RS03390GCF_002303425#BGU60_RS03390
RROmpR

22 020-22 691 nt · Reverse (-)

Old locus BGU60_03280RefSeq WP_003422026.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2642815Run 6 · HK · 4 sequences
Representative sequenceGCF_002303425#BGU60_RS03385The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2642815

Simplified PFAM architecture for HKOC_2642815

PFAM domain coverage: 225 / 376 aa (59.8%)

1 aa376 aa
HAMP: 80-131 aaHAMPHisKA: 156-221 aaHisKAHATPase_c: 268-374 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[80-131] | HisKA[156-221] | HATPase_c[268-374]
  • Domain count: 3
  • Matched identifier: HKOC_2642815
  • Positioned domains: HAMP 80-131 ; HisKA 156-221 ; HATPase_c 268-374
Cluster members and taxonomy
Visualization

Representative gene: GCF_002303425#BGU60_RS03385

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303425
AssemblyASM230342v1 · Contighaploid
Genome composition4 026 332 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key