Gene detail

BGU53_RS09255

Histidine kinase, Classic

Clostridioides difficile · GCF_002303305

ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303305#BGU53_RS09255Stable P2CS identifier used across views.
GenomeGCF_002303305Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1338518Run 6 · 305 sequences · id 100% · cov 80%
External referencesWP_003417858.1 · D5Q0A9 · MIST4 BGU53_RS09255RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa535 aa
HisKA: 304-371 aa (68 aa)1HATPase_c: 416-525 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw tokenHisKA:304:0.000000000000135:371:68:64
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw tokenHATPase_c:416:6.54e-31:525:110:109
  • Raw architecture: HisKA:304:0.000000000000135:371:68:64#HATPase_c:416:6.54e-31:525:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303305::NZ_MPJO01000014.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span46326-48628Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU53_09135RefSeq proteinWP_003417858.1
Context group IDGCF_002303305::NZ_MPJO01000014.1::G00029
Context members
BGU53_RS09255BGU53_RS09260
Partner locus tags
BGU53_RS09255BGU53_RS09260
Partner old locus tags
BGU53_09135BGU53_09140
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003417858.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0A9Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0A9_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU53_RS09255Primary locus identifier stored in the genes table.
Old locus tagBGU53_09135Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPJO01000014.1Sequence record reported by the local genomic context database.
Genomic interval46 326-47 933 nt1 608 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span46 326-48 628 ntGCF_002303305::NZ_MPJO01000014.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303305::NZ_MPJO01000014.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPJO01000014.1All displayed genes belong to this local TCS context.
Neighborhood span46 326-48 628 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
46 326 nt48 628 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU53_RS09255GCF_002303305#BGU53_RS09255
HKClassicCurrent focus

46 326-47 933 nt · Forward (+)

Old locus BGU53_09135RefSeq WP_003417858.1
BGU53_RS09260GCF_002303305#BGU53_RS09260
RROmpR

47 924-48 628 nt · Forward (+)

Old locus BGU53_09140RefSeq WP_003417859.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1338518Run 6 · HK · 305 sequences
Representative sequenceGCF_000164175#HMPREF0220_RS08690Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1338518

Simplified PFAM architecture for HKOC_1338518

PFAM domain coverage: 286 / 535 aa (53.5%)

1 aa535 aa
DUF4118: 32-139 aaDUF4118HisKA: 304-371 aaHisKAHATPase_c: 416-525 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
  • Domain count: 3
  • Matched identifier: HKOC_1338518
  • Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164175#HMPREF0220_RS08690

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303305
AssemblyASM230330v1 · Contighaploid
Genome composition3 958 605 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key