Gene detail

BGV22_RS06370

Histidine kinase, Classic

Clostridioides difficile · GCF_002303125

ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303125#BGV22_RS06370Stable P2CS identifier used across views.
GenomeGCF_002303125Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1338673Run 6 · 98 sequences · id 100% · cov 80%
External referencesWP_021366190.1 · A0A069APS3 · MIST4 BGV22_RS06370RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa535 aa
HisKA: 304-371 aa (68 aa)1HATPase_c: 416-525 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw tokenHisKA:304:0.000000000000118:371:68:64
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw tokenHATPase_c:416:2.2e-31:525:110:109
  • Raw architecture: HisKA:304:0.000000000000118:371:68:64#HATPase_c:416:2.2e-31:525:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303125::NZ_MPFU01000004.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span105104-107406Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGV22_06320RefSeq proteinWP_021366190.1
Context group IDGCF_002303125::NZ_MPFU01000004.1::G00018
Context members
BGV22_RS06365BGV22_RS06370
Partner locus tags
BGV22_RS06365BGV22_RS06370
Partner old locus tags
BGV22_06315BGV22_06320
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366190.1Primary protein accession used for annex mappings.
UniProt accessionA0A069APS3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069APS3_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGV22_RS06370Primary locus identifier stored in the genes table.
Old locus tagBGV22_06320Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPFU01000004.1Sequence record reported by the local genomic context database.
Genomic interval105 799-107 406 nt1 608 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span105 104-107 406 ntGCF_002303125::NZ_MPFU01000004.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303125::NZ_MPFU01000004.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPFU01000004.1All displayed genes belong to this local TCS context.
Neighborhood span105 104-107 406 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
105 104 nt107 406 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGV22_RS06365GCF_002303125#BGV22_RS06365
RROmpR

105 104-105 808 nt · Reverse (-)

Old locus BGV22_06315RefSeq WP_003439080.1
BGV22_RS06370GCF_002303125#BGV22_RS06370
HKClassicCurrent focus

105 799-107 406 nt · Reverse (-)

Old locus BGV22_06320RefSeq WP_021366190.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1338673Run 6 · HK · 98 sequences
Representative sequenceGCF_000448765#QC5_RS02360Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1338673

Simplified PFAM architecture for HKOC_1338673

PFAM domain coverage: 286 / 535 aa (53.5%)

1 aa535 aa
DUF4118: 32-139 aaDUF4118HisKA: 304-371 aaHisKAHATPase_c: 416-525 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
  • Domain count: 3
  • Matched identifier: HKOC_1338673
  • Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS02360

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303125
AssemblyASM230312v1 · Contighaploid
Genome composition4 277 963 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key