Gene detail

BGV22_RS04430

Histidine kinase, Classic

Clostridioides difficile · GCF_002303125

ClassHKTypeClassicLength334 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303125#BGV22_RS04430Stable P2CS identifier used across views.
GenomeGCF_002303125Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2849842Run 6 · 127 sequences · id 100% · cov 80%
External referencesWP_021366592.1 · A0A069ATB7 · MIST4 BGV22_RS04430RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length334 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 334 aa (50.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BGV22_RS04430
Domain-by-domain annotation2 items
1 HisKA#1
118-178 aa · 61 aa · 18.3% of protein
Raw tokenHisKA:118:0.00000713:178:63:64
2 HATPase_c#2
224-331 aa · 108 aa · 32.3% of protein
Raw tokenHATPase_c:224:2.76e-25:331:108:109
  • Raw architecture: HisKA:118:0.00000713:178:63:64#HATPase_c:224:2.76e-25:331:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303125::NZ_MPFU01000002.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span485064-486766Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGV22_04400RefSeq proteinWP_021366592.1
Context group IDGCF_002303125::NZ_MPFU01000002.1::G00012
Context members
BGV22_RS04430BGV22_RS04435
Partner locus tags
BGV22_RS04430BGV22_RS04435
Partner old locus tags
BGV22_04400BGV22_04405
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366592.1Primary protein accession used for annex mappings.
UniProt accessionA0A069ATB7Primary UniProt accession resolved in the annex database.
UniProt IDA0A069ATB7_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGV22_RS04430Primary locus identifier stored in the genes table.
Old locus tagBGV22_04400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPFU01000002.1Sequence record reported by the local genomic context database.
Genomic interval485 064-486 068 nt1 005 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span485 064-486 766 ntGCF_002303125::NZ_MPFU01000002.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303125::NZ_MPFU01000002.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPFU01000002.1All displayed genes belong to this local TCS context.
Neighborhood span485 064-486 766 nt1 703 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
485 064 nt486 766 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGV22_RS04430GCF_002303125#BGV22_RS04430
HKClassicCurrent focus

485 064-486 068 nt · Reverse (-)

Old locus BGV22_04400RefSeq WP_021366592.1
BGV22_RS04435GCF_002303125#BGV22_RS04435
RROmpR

486 092-486 766 nt · Reverse (-)

Old locus BGV22_04405RefSeq WP_003436727.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2849842Run 6 · HK · 127 sequences
Representative sequenceGCF_000448765#QC5_RS07515Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2849842

Simplified PFAM architecture for HKOC_2849842

PFAM domain coverage: 108 / 334 aa (32.3%)

1 aa334 aa
HATPase_c: 224-331 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[224-331]
  • Domain count: 1
  • Matched identifier: HKOC_2849842
  • Positioned domains: HATPase_c 224-331
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS07515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303125
AssemblyASM230312v1 · Contighaploid
Genome composition4 277 963 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key