Gene detail

BGV21_RS17990

Histidine kinase, Classic

Clostridioides difficile · GCF_002303105

ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303105#BGV21_RS17990Stable P2CS identifier used across views.
GenomeGCF_002303105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2084081Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_095926208.1 · MIST4 BGV21_RS17990RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 439 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
HAMP: 155-221 aa (67 aa)1HisKA: 232-290 aa (59 aa)2HATPase_c: 347-438 aa (92 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
155-221 aa · 67 aa · 15.3% of protein
Raw tokenHAMP:155:0.000000000643:221:70:69
2 HisKA#2
232-290 aa · 59 aa · 13.4% of protein
Raw tokenHisKA:232:0.000000000226:290:59:64
3 HATPase_c#3
347-438 aa · 92 aa · 21.0% of protein
Raw tokenHATPase_c:347:0.0000000155:438:108:109
  • Raw architecture: HAMP:155:0.000000000643:221:70:69#HisKA:232:0.000000000226:290:59:64#HATPase_c:347:0.0000000155:438:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303105::NZ_MPFT01000095.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4796-6812Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGV21_17730RefSeq proteinWP_095926208.1
Context group IDGCF_002303105::NZ_MPFT01000095.1::G00054
Context members
BGV21_RS17985BGV21_RS17990
Partner locus tags
BGV21_RS17985BGV21_RS17990
Partner old locus tags
BGV21_17725BGV21_17730
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_095926208.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGV21_RS17990Primary locus identifier stored in the genes table.
Old locus tagBGV21_17730Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPFT01000095.1Sequence record reported by the local genomic context database.
Genomic interval5 493-6 812 nt1 320 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 796-6 812 ntGCF_002303105::NZ_MPFT01000095.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303105::NZ_MPFT01000095.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPFT01000095.1All displayed genes belong to this local TCS context.
Neighborhood span4 796-6 812 nt2 017 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 796 nt6 812 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGV21_RS17985GCF_002303105#BGV21_RS17985
RROmpR

4 796-5 500 nt · Forward (+)

Old locus BGV21_17725RefSeq WP_003426384.1
BGV21_RS17990GCF_002303105#BGV21_RS17990
HKClassicCurrent focus

5 493-6 812 nt · Forward (+)

Old locus BGV21_17730RefSeq WP_095926208.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2084081Run 6 · HK · 1 sequences
Representative sequenceGCF_002303105#BGV21_RS17990The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2084081

Simplified PFAM architecture for HKOC_2084081

PFAM domain coverage: 169 / 439 aa (38.5%)

1 aa439 aa
HAMP: 176-220 aaHAMPHisKA: 234-290 aaHisKAHATPase_c_5: 369-435 aaHATPase_c_5
HAMPHisKAHATPase_c_5
  • Simplified architecture: HAMP + HisKA + HATPase_c_5
  • Raw architecture: HAMP[176-220] | HisKA[234-290] | HATPase_c_5[369-435]
  • Domain count: 3
  • Matched identifier: HKOC_2084081
  • Positioned domains: HAMP 176-220 ; HisKA 234-290 ; HATPase_c_5 369-435
Cluster members and taxonomy
Visualization

Representative gene: GCF_002303105#BGV21_RS17990

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303105
AssemblyASM230310v1 · Contighaploid
Genome composition4 397 851 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 45 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key