Gene detail

BGV18_RS17775

Histidine kinase, Classic

Clostridioides difficile · GCF_002303045

ClassHKTypeClassicLength899 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002303045#BGV18_RS17775Stable P2CS identifier used across views.
GenomeGCF_002303045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0407373Run 6 · 232 sequences · id 100% · cov 80%
External referencesWP_003428621.1 · A0A9P3TYP6 · MIST4 BGV18_RS17775RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length899 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage514 / 899 aa (57.2%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BGV18_RS17775
Domain-by-domain annotation4 items
1 KdpD#1
22-230 aa · 209 aa · 23.2% of protein
Raw tokenKdpD:22:4.34e-134:230:209:210
2 GAF_3#2
533-656 aa · 124 aa · 13.8% of protein
Raw tokenGAF_3:533:0.00000107:656:129:129
3 HisKA#3
676-743 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:676:0.0000000000036:743:68:64
4 HATPase_c#4
787-899 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:787:1.61e-30:899:113:109
  • Raw architecture: KdpD:22:4.34e-134:230:209:210#GAF_3:533:0.00000107:656:129:129#HisKA:676:0.0000000000036:743:68:64#HATPase_c:787:1.61e-30:899:113:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002303045::NZ_MPFQ01000032.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21086-24520Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGV18_17605RefSeq proteinWP_003428621.1
Context group IDGCF_002303045::NZ_MPFQ01000032.1::G00053
Context members
BGV18_RS17770BGV18_RS17775
Partner locus tags
BGV18_RS17770BGV18_RS17775
Partner old locus tags
BGV18_17600BGV18_17605
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003428621.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3TYP6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3TYP6_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGV18_RS17775Primary locus identifier stored in the genes table.
Old locus tagBGV18_17605Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPFQ01000032.1Sequence record reported by the local genomic context database.
Genomic interval21 821-24 520 nt2 700 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span21 086-24 520 ntGCF_002303045::NZ_MPFQ01000032.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002303045::NZ_MPFQ01000032.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPFQ01000032.1All displayed genes belong to this local TCS context.
Neighborhood span21 086-24 520 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 086 nt24 520 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGV18_RS17770GCF_002303045#BGV18_RS17770
RROmpR

21 086-21 784 nt · Reverse (-)

Old locus BGV18_17600RefSeq WP_003428622.1
BGV18_RS17775GCF_002303045#BGV18_RS17775
HKClassicCurrent focus

21 821-24 520 nt · Reverse (-)

Old locus BGV18_17605RefSeq WP_003428621.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0407373Run 6 · HK · 232 sequences
Representative sequenceGCF_000210395#CDM68_RS09595Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0407373

Simplified PFAM architecture for HKOC_0407373

PFAM domain coverage: 494 / 899 aa (54.9%)

1 aa899 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0407373
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS09595

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 232 total members. Page 1 / 5.

GCF_000210395#CDM68_RS09595 (representative)
CDM68_RS09595 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000235825#HMPREF1122_RS08130
HMPREF1122_RS08130 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000235925#HMPREF1123_RS06145
HMPREF1123_RS06145 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000449945#QIG_RS09075
QIG_RS09075 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000452125#QUY_RS09375
QUY_RS09375 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000452165#QW3_RS09705
QW3_RS09705 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000530915#BN167_RS09775
BN167_RS09775 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_000531625#BN168_RS09655
BN168_RS09655 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_001971875#BER36_RS10105
BER36_RS10105 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_001972195#BER37_RS09715
BER37_RS09715 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002301435#BGU22_RS07950
BGU22_RS07950 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002301555#BGU29_RS17650
BGU29_RS17650 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002302945#BGV12_RS13480
BGV12_RS13480 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002303045#BGV18_RS17775
BGV18_RS17775 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002303155#BGV23_RS10780
BGV23_RS10780 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002303485#BGU64_RS02300
BGU64_RS02300 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_002940825#AWN77_RS17640
AWN77_RS17640 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003095675#DDG63_RS10135
DDG63_RS10135 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003095695#DDG61_RS10410
DDG61_RS10410 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003324015#DVA89_RS08960
DVA89_RS08960 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003324025#DVA88_RS07725
DVA88_RS07725 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003324035#DVA87_RS01120
DVA87_RS01120 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326835#DVA92_RS01675
DVA92_RS01675 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326845#DVA91_RS08105
DVA91_RS08105 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326875#DVA94_RS09120
DVA94_RS09120 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326885#DVA93_RS00275
DVA93_RS00275 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326915#DVA96_RS07635
DVA96_RS07635 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326935#DVA97_RS03855
DVA97_RS03855 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326945#DVA98_RS08190
DVA98_RS08190 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326965#DVA99_RS13450
DVA99_RS13450 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003326985#DVB00_RS08760
DVB00_RS08760 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327015#DVB04_RS05565
DVB04_RS05565 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327025#DVB06_RS04885
DVB06_RS04885 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327055#DVB02_RS12625
DVB02_RS12625 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327065#DVB01_RS08690
DVB01_RS08690 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327105#DVB12_RS19230
DVB12_RS19230 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327115#DVB09_RS09120
DVB09_RS09120 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327145#DVB10_RS07320
DVB10_RS07320 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327165#DVB07_RS17205
DVB07_RS17205 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327185#DVB14_RS01940
DVB14_RS01940 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327205#DVB16_RS11495
DVB16_RS11495 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327215#DVB15_RS08140
DVB15_RS08140 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327245#DVB19_RS12765
DVB19_RS12765 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327265#DVB18_RS07725
DVB18_RS07725 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327345#DVB13_RS08095
DVB13_RS08095 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327365#DVB11_RS02975
DVB11_RS02975 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003327755#DVB17_RS19215
DVB17_RS19215 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003328455#DR993_RS10200
DR993_RS10200 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_003482255#CDIF29627_RS10025
CDIF29627_RS10025 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6
GCF_004313745#E0N65_RS00050
E0N65_RS00050 · HK · Classic
RefSeq: WP_003428621.1
UniProt: A0A9P3TYP6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002303045
AssemblyASM230304v1 · Contighaploid
Genome composition4 198 488 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key