Gene detail

BGU99_RS00185

Histidine kinase, Classic

Clostridioides difficile · GCF_002302245

ClassHKTypeClassicLength335 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002302245#BGU99_RS00185Stable P2CS identifier used across views.
GenomeGCF_002302245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2848168Run 6 · 177 sequences · id 100% · cov 80%
External referencesWP_003439831.1 · A0A6N2YW64 · MIST4 BGU99_RS00185RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length335 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage165 / 335 aa (49.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BGU99_RS00185
Domain-by-domain annotation2 items
1 HisKA#1
122-175 aa · 54 aa · 16.1% of protein
Raw tokenHisKA:122:0.00000357:175:60:64
2 HATPase_c#2
221-331 aa · 111 aa · 33.1% of protein
Raw tokenHATPase_c:221:9.01e-21:331:111:109
  • Raw architecture: HisKA:122:0.00000357:175:60:64#HATPase_c:221:9.01e-21:331:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002302245::NZ_MPEK01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41211-42886Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU99_00185RefSeq proteinWP_003439831.1
Context group IDGCF_002302245::NZ_MPEK01000001.1::G00001
Context members
BGU99_RS00180BGU99_RS00185
Partner locus tags
BGU99_RS00180BGU99_RS00185
Partner old locus tags
BGU99_00180BGU99_00185
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003439831.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N2YW64Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N2YW64_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU99_RS00185Primary locus identifier stored in the genes table.
Old locus tagBGU99_00185Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPEK01000001.1Sequence record reported by the local genomic context database.
Genomic interval41 879-42 886 nt1 008 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span41 211-42 886 ntGCF_002302245::NZ_MPEK01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002302245::NZ_MPEK01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPEK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span41 211-42 886 nt1 676 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 211 nt42 886 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU99_RS00180GCF_002302245#BGU99_RS00180
RROmpR

41 211-41 882 nt · Forward (+)

Old locus BGU99_00180RefSeq WP_021367068.1
BGU99_RS00185GCF_002302245#BGU99_RS00185
HKClassicCurrent focus

41 879-42 886 nt · Forward (+)

Old locus BGU99_00185RefSeq WP_003439831.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2848168Run 6 · HK · 177 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS03220Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2848168

Simplified PFAM architecture for HKOC_2848168

PFAM domain coverage: 110 / 335 aa (32.8%)

1 aa335 aa
HATPase_c: 221-330 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[221-330]
  • Domain count: 1
  • Matched identifier: HKOC_2848168
  • Positioned domains: HATPase_c 221-330
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS03220

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002302245
AssemblyASM230224v1 · Contighaploid
Genome composition4 077 722 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key