Gene detail

BGU92_RS12270

Histidine kinase, Classic

Clostridioides difficile · GCF_002302165

ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002302165#BGU92_RS12270Stable P2CS identifier used across views.
GenomeGCF_002302165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2857938Run 6 · 1482 sequences · id 100% · cov 80%
External referencesWP_003434897.1 · Q181I8 · MIST4 BGU92_RS12270RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
HisKA: 117-177 aa (61 aa)1HATPase_c: 222-328 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw tokenHisKA:117:0.000000000161:177:61:64
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw tokenHATPase_c:222:6.69e-24:328:107:109
  • Raw architecture: HisKA:117:0.000000000161:177:61:64#HATPase_c:222:6.69e-24:328:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002302165::NZ_MPEY01000012.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span112604-114266Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU92_12165RefSeq proteinWP_003434897.1
Context group IDGCF_002302165::NZ_MPEY01000012.1::G00041
Context members
BGU92_RS12265BGU92_RS12270
Partner locus tags
BGU92_RS12265BGU92_RS12270
Partner old locus tags
BGU92_12160BGU92_12165
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434897.1Primary protein accession used for annex mappings.
UniProt accessionQ181I8Primary UniProt accession resolved in the annex database.
UniProt IDQ181I8_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU92_RS12270Primary locus identifier stored in the genes table.
Old locus tagBGU92_12165Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MPEY01000012.1Sequence record reported by the local genomic context database.
Genomic interval113 277-114 266 nt990 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span112 604-114 266 ntGCF_002302165::NZ_MPEY01000012.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002302165::NZ_MPEY01000012.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MPEY01000012.1All displayed genes belong to this local TCS context.
Neighborhood span112 604-114 266 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
112 604 nt114 266 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU92_RS12265GCF_002302165#BGU92_RS12265
RROmpR

112 604-113 290 nt · Forward (+)

Old locus BGU92_12160RefSeq WP_003434895.1
BGU92_RS12270GCF_002302165#BGU92_RS12270
HKClassicCurrent focus

113 277-114 266 nt · Forward (+)

Old locus BGU92_12165RefSeq WP_003434897.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2857938Run 6 · HK · 1482 sequences
Representative sequenceGCF_000009205#CD630_RS19070Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2857938

Simplified PFAM architecture for HKOC_2857938

PFAM domain coverage: 169 / 329 aa (51.4%)

1 aa329 aa
HisKA: 116-177 aaHisKAHATPase_c: 222-328 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[116-177] | HATPase_c[222-328]
  • Domain count: 2
  • Matched identifier: HKOC_2857938
  • Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS19070

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002302165
AssemblyASM230216v1 · Contighaploid
Genome composition4 079 871 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key