Gene detail

BGU21_RS18645

Histidine kinase, Classic

Clostridioides difficile · GCF_002301705

ClassHKTypeClassicLength430 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002301705#BGU21_RS18645Stable P2CS identifier used across views.
GenomeGCF_002301705Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2172345Run 6 · 146 sequences · id 100% · cov 80%
External referencesWP_021364213.1 · A0A7G9GSI8 · MIST4 BGU21_RS18645RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length430 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 430 aa (41.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BGU21_RS18645
Domain-by-domain annotation2 items
1 HisKA#1
207-272 aa · 66 aa · 15.3% of protein
Raw tokenHisKA:207:0.000000000000035:272:66:64
2 HATPase_c#2
320-430 aa · 111 aa · 25.8% of protein
Raw tokenHATPase_c:320:1.3e-27:430:111:109
  • Raw architecture: HisKA:207:0.000000000000035:272:66:64#HATPase_c:320:1.3e-27:430:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002301705::NZ_MOPV01000044.1::G00056
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2953-4925Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU21_18435RefSeq proteinWP_021364213.1
Context group IDGCF_002301705::NZ_MOPV01000044.1::G00056
Context members
BGU21_RS18645BGU21_RS18650
Partner locus tags
BGU21_RS18645BGU21_RS18650
Partner old locus tags
BGU21_18435BGU21_18440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021364213.1Primary protein accession used for annex mappings.
UniProt accessionA0A7G9GSI8Primary UniProt accession resolved in the annex database.
UniProt IDA0A7G9GSI8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU21_RS18645Primary locus identifier stored in the genes table.
Old locus tagBGU21_18435Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOPV01000044.1Sequence record reported by the local genomic context database.
Genomic interval2 953-4 245 nt1 293 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 953-4 925 ntGCF_002301705::NZ_MOPV01000044.1::G00056

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002301705::NZ_MOPV01000044.1::G00056

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOPV01000044.1All displayed genes belong to this local TCS context.
Neighborhood span2 953-4 925 nt1 973 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 953 nt4 925 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU21_RS18645GCF_002301705#BGU21_RS18645
HKClassicCurrent focus

2 953-4 245 nt · Reverse (-)

Old locus BGU21_18435RefSeq WP_021364213.1
BGU21_RS18650GCF_002301705#BGU21_RS18650
RROmpR

4 239-4 925 nt · Reverse (-)

Old locus BGU21_18440RefSeq WP_021364217.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2172345Run 6 · HK · 146 sequences
Representative sequenceGCF_000448745#QC1_RS03045Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2172345

Simplified PFAM architecture for HKOC_2172345

PFAM domain coverage: 174 / 430 aa (40.5%)

1 aa430 aa
HisKA: 208-272 aaHisKAHATPase_c: 321-429 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[208-272] | HATPase_c[321-429]
  • Domain count: 2
  • Matched identifier: HKOC_2172345
  • Positioned domains: HisKA 208-272 ; HATPase_c 321-429
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS03045

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002301705
AssemblyASM230170v1 · Contighaploid
Genome composition4 337 457 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key