Gene detail

BGU20_RS01310

Histidine kinase, Classic

Clostridioides difficile · GCF_002301695

ClassHKTypeClassicLength900 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002301695#BGU20_RS01310Stable P2CS identifier used across views.
GenomeGCF_002301695Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0405642Run 6 · 304 sequences · id 100% · cov 80%
External referencesWP_003423900.1 · D5Q4N8 · MIST4 BGU20_RS01310RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length900 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage514 / 900 aa (57.1%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa900 aa
KdpD: 22-230 aa (209 aa)1GAF_3: 533-656 aa (124 aa)2HisKA: 676-743 aa (68 aa)3HATPase_c: 787-899 aa (113 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
22-230 aa · 209 aa · 23.2% of protein
Raw tokenKdpD:22:1.62e-133:230:209:210
2 GAF_3#2
533-656 aa · 124 aa · 13.8% of protein
Raw tokenGAF_3:533:0.000000213:656:129:129
3 HisKA#3
676-743 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:676:0.0000000000054:743:68:64
4 HATPase_c#4
787-899 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:787:2.18e-30:899:113:109
  • Raw architecture: KdpD:22:1.62e-133:230:209:210#GAF_3:533:0.000000213:656:129:129#HisKA:676:0.0000000000054:743:68:64#HATPase_c:787:2.18e-30:899:113:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002301695::NZ_MOPU01000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span251989-255423Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU20_01245RefSeq proteinWP_003423900.1
Context group IDGCF_002301695::NZ_MOPU01000001.1::G00005
Context members
BGU20_RS01305BGU20_RS01310
Partner locus tags
BGU20_RS01305BGU20_RS01310
Partner old locus tags
BGU20_01240BGU20_01245
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003423900.1Primary protein accession used for annex mappings.
UniProt accessionD5Q4N8Primary UniProt accession resolved in the annex database.
UniProt IDD5Q4N8_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU20_RS01310Primary locus identifier stored in the genes table.
Old locus tagBGU20_01245Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOPU01000001.1Sequence record reported by the local genomic context database.
Genomic interval252 721-255 423 nt2 703 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span251 989-255 423 ntGCF_002301695::NZ_MOPU01000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002301695::NZ_MOPU01000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOPU01000001.1All displayed genes belong to this local TCS context.
Neighborhood span251 989-255 423 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
251 989 nt255 423 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU20_RS01305GCF_002301695#BGU20_RS01305
RROmpR

251 989-252 687 nt · Reverse (-)

Old locus BGU20_01240RefSeq WP_003423901.1
BGU20_RS01310GCF_002301695#BGU20_RS01310
HKClassicCurrent focus

252 721-255 423 nt · Reverse (-)

Old locus BGU20_01245RefSeq WP_003423900.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0405642Run 6 · HK · 304 sequences
Representative sequenceGCF_000155065#QAE_RS0209080Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0405642

Simplified PFAM architecture for HKOC_0405642

PFAM domain coverage: 494 / 900 aa (54.9%)

1 aa900 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0405642
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0209080

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 304 total members. Page 1 / 7.

GCF_000155065#QAE_RS0209080 (representative)
QAE_RS0209080 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_000164175#HMPREF0220_RS13390
HMPREF0220_RS13390 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_000164655#HMPREF0219_RS05085
HMPREF0219_RS05085 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_000210435#CDM120_RS09560
CDM120_RS09560 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_000499505#BN164_RS08460
BN164_RS08460 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_000531165#BN166_RS08520
BN166_RS08520 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_000582865#BN165_RS08590
BN165_RS08590 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_001050575#BN163_RS08740
BN163_RS08740 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_001972065#BER35_RS09770
BER35_RS09770 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_001972115#BER34_RS10115
BER34_RS10115 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002301695#BGU20_RS01310
BGU20_RS01310 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002302685#BGU93_RS10495
BGU93_RS10495 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002303305#BGU53_RS00660
BGU53_RS00660 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002303425#BGU60_RS02885
BGU60_RS02885 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002352505#V439_RS09390
V439_RS09390 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002412385#V438_RS09465
V438_RS09465 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002946515#C4E25_RS09355
C4E25_RS09355 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002946535#C4E42_RS09835
C4E42_RS09835 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_002946555#C4E26_RS09355
C4E26_RS09355 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_003482165#CDIF29020_RS09815
CDIF29020_RS09815 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_003482365#CDIF29747_RS09355
CDIF29747_RS09355 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_003697205#EBB60_RS09660
EBB60_RS09660 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_003697225#EBL90_RS09805
EBL90_RS09805 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_003697245#EBL91_RS09145
EBL91_RS09145 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_004318565#E0Q96_RS05000
E0Q96_RS05000 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_004318785#E0Q93_RS08445
E0Q93_RS08445 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_008579085#F6C11_RS05700
F6C11_RS05700 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_009362915#FTB24_RS09710
FTB24_RS09710 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_012952655#HCN89_RS10075
HCN89_RS10075 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_015351855#ITI91_RS09605
ITI91_RS09605 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_015352255#ITJ05_RS02215
ITJ05_RS02215 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_015732535#CDIF101085_RS09170
CDIF101085_RS09170 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016766955#JMW53_RS17410
JMW53_RS17410 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016766975#JMW50_RS06200
JMW50_RS06200 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016766995#JMW52_RS11310
JMW52_RS11310 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016767015#JMW49_RS17170
JMW49_RS17170 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016767035#JMW55_RS14145
JMW55_RS14145 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016767055#JMW51_RS11570
JMW51_RS11570 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016767095#JMW48_RS05800
JMW48_RS05800 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016767115#JMW47_RS02380
JMW47_RS02380 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_016767135#JMW46_RS00240
JMW46_RS00240 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_017592625#J5O10_RS09160
J5O10_RS09160 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_018603395#KK111_RS09290
KK111_RS09290 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_018603455#KK110_RS09285
KK110_RS09285 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_018603475#KK112_RS09275
KK112_RS09275 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_018884725#E1H40_RS09080
E1H40_RS09080 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_019427665#K1N48_RS05200
K1N48_RS05200 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_019427725#K1N54_RS11795
K1N54_RS11795 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_019931025#K8P06_RS01210
K8P06_RS01210 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8
GCF_020297505#LA365_RS03560
LA365_RS03560 · HK · Classic
RefSeq: WP_003423900.1
UniProt: D5Q4N8

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002301695
AssemblyASM230169v1 · Contighaploid
Genome composition3 968 957 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key