Gene detail

BGU18_RS02535

Histidine kinase, Classic

Clostridioides difficile · GCF_002301395

ClassHKTypeClassicLength334 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002301395#BGU18_RS02535Stable P2CS identifier used across views.
GenomeGCF_002301395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2850083Run 6 · 29 sequences · id 100% · cov 80% · representative
External referencesWP_021364746.1 · A0A9X8RIB1 · MIST4 BGU18_RS02535RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length334 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage157 / 334 aa (47.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa334 aa
HisKA: 123-170 aa (48 aa)1HATPase_c: 216-324 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
123-170 aa · 48 aa · 14.4% of protein
Raw tokenHisKA:123:0.000000784:170:53:64
2 HATPase_c#2
216-324 aa · 109 aa · 32.6% of protein
Raw tokenHATPase_c:216:1.09e-22:324:109:109
  • Raw architecture: HisKA:123:0.000000784:170:53:64#HATPase_c:216:1.09e-22:324:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002301395::NZ_MOPS01000002.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span247975-249681Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU18_02520RefSeq proteinWP_021364746.1
Context group IDGCF_002301395::NZ_MOPS01000002.1::G00005
Context members
BGU18_RS02535BGU18_RS02540
Partner locus tags
BGU18_RS02535BGU18_RS02540
Partner old locus tags
BGU18_02520BGU18_02525
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021364746.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RIB1Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RIB1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU18_RS02535Primary locus identifier stored in the genes table.
Old locus tagBGU18_02520Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOPS01000002.1Sequence record reported by the local genomic context database.
Genomic interval247 975-248 979 nt1 005 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span247 975-249 681 ntGCF_002301395::NZ_MOPS01000002.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002301395::NZ_MOPS01000002.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOPS01000002.1All displayed genes belong to this local TCS context.
Neighborhood span247 975-249 681 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
247 975 nt249 681 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU18_RS02535GCF_002301395#BGU18_RS02535
HKClassicCurrent focus

247 975-248 979 nt · Reverse (-)

Old locus BGU18_02520RefSeq WP_021364746.1
BGU18_RS02540GCF_002301395#BGU18_RS02540
RROmpR

248 989-249 681 nt · Reverse (-)

Old locus BGU18_02525RefSeq WP_003429090.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2850083Run 6 · HK · 29 sequences
Representative sequenceGCF_002301395#BGU18_RS02535The current gene is the representative for this cluster.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2850083

Simplified PFAM architecture for HKOC_2850083

PFAM domain coverage: 109 / 334 aa (32.6%)

1 aa334 aa
HATPase_c: 217-325 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[217-325]
  • Domain count: 1
  • Matched identifier: HKOC_2850083
  • Positioned domains: HATPase_c 217-325
Cluster members and taxonomy
Visualization

Representative gene: GCF_002301395#BGU18_RS02535

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002301395
AssemblyASM230139v1 · Contighaploid
Genome composition4 389 482 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key