Gene detail

BGU12_RS14420

Histidine kinase, Classic

Clostridioides difficile · GCF_002301185

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002301185#BGU12_RS14420Stable P2CS identifier used across views.
GenomeGCF_002301185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557909Run 6 · 301 sequences · id 100% · cov 80%
External referencesWP_021364232.1 · A0A9X8RLC8 · MIST4 BGU12_RS14420RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BGU12_RS14420
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000572:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000519:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:9.75e-21:382:106:109
  • Raw architecture: HAMP:84:0.000000572:152:70:69#HisKA:164:0.0000000519:217:54:64#HATPase_c:278:9.75e-21:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002301185::NZ_MOPM01000015.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span100121-101943Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU12_14270RefSeq proteinWP_021364232.1
Context group IDGCF_002301185::NZ_MOPM01000015.1::G00045
Context members
BGU12_RS14420BGU12_RS14425
Partner locus tags
BGU12_RS14420BGU12_RS14425
Partner old locus tags
BGU12_14270BGU12_14275
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021364232.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RLC8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RLC8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU12_RS14420Primary locus identifier stored in the genes table.
Old locus tagBGU12_14270Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOPM01000015.1Sequence record reported by the local genomic context database.
Genomic interval100 121-101 281 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span100 121-101 943 ntGCF_002301185::NZ_MOPM01000015.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002301185::NZ_MOPM01000015.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOPM01000015.1All displayed genes belong to this local TCS context.
Neighborhood span100 121-101 943 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
100 121 nt101 943 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU12_RS14420GCF_002301185#BGU12_RS14420
HKClassicCurrent focus

100 121-101 281 nt · Reverse (-)

Old locus BGU12_14270RefSeq WP_021364232.1
BGU12_RS14425GCF_002301185#BGU12_RS14425
RROmpR

101 269-101 943 nt · Reverse (-)

Old locus BGU12_14275RefSeq WP_021364234.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557909Run 6 · HK · 301 sequences
Representative sequenceGCF_000448745#QC1_RS03545Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557909

Simplified PFAM architecture for HKOC_2557909

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557909
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS03545

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002301185
AssemblyASM230118v1 · Contighaploid
Genome composition4 099 996 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key