Gene detail

BGU08_RS00290

Histidine kinase, Classic

Clostridioides difficile · GCF_002301105

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002301105#BGU08_RS00290Stable P2CS identifier used across views.
GenomeGCF_002301105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440982Run 6 · 99 sequences · id 100% · cov 80%
External referencesWP_021367036.1 · A0A069A9I9 · MIST4 BGU08_RS00290RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BGU08_RS00290
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:2.31e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.00000000147:400:108:109
  • Raw architecture: His_kinase:205:2.31e-31:283:80:80#HATPase_c:300:0.00000000147:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002301105::NZ_MOPI01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span63462-65439Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU08_00290RefSeq proteinWP_021367036.1
Context group IDGCF_002301105::NZ_MOPI01000001.1::G00002
Context members
BGU08_RS00290BGU08_RS00295
Partner locus tags
BGU08_RS00290BGU08_RS00295
Partner old locus tags
BGU08_00290BGU08_00295
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021367036.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A9I9Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A9I9_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU08_RS00290Primary locus identifier stored in the genes table.
Old locus tagBGU08_00290Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOPI01000001.1Sequence record reported by the local genomic context database.
Genomic interval63 462-64 664 nt1 203 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span63 462-65 439 ntGCF_002301105::NZ_MOPI01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002301105::NZ_MOPI01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOPI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span63 462-65 439 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
63 462 nt65 439 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU08_RS00290GCF_002301105#BGU08_RS00290
HKClassicCurrent focus

63 462-64 664 nt · Forward (+)

Old locus BGU08_00290RefSeq WP_021367036.1
BGU08_RS00295GCF_002301105#BGU08_RS00295
RRLytTR

64 669-65 439 nt · Forward (+)

Old locus BGU08_00295RefSeq WP_009897796.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440982Run 6 · HK · 99 sequences
Representative sequenceGCF_000448765#QC5_RS13140Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440982

Simplified PFAM architecture for HKOC_2440982

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440982
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS13140

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002301105
AssemblyASM230110v1 · Contighaploid
Genome composition4 123 370 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key