Gene detail

BGU03_RS14670

Histidine kinase, Classic

Clostridioides difficile · GCF_002301035

ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002301035#BGU03_RS14670Stable P2CS identifier used across views.
GenomeGCF_002301035Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2180212Run 6 · 2508 sequences · id 100% · cov 80%
External referencesWP_003426968.1 · A0A0H3NE71 · MIST4 BGU03_RS14670RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage340 / 429 aa (79.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa429 aa
HAMP: 6-74 aa (69 aa)1PAS_9: 96-195 aa (100 aa)2HisKA: 202-268 aa (67 aa)3HATPase_c: 319-422 aa (104 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
6-74 aa · 69 aa · 16.1% of protein
Raw tokenHAMP:6:0.000000244:74:69:69
2 PAS_9#2
96-195 aa · 100 aa · 23.3% of protein
Raw tokenPAS_9:96:0.00000117:195:103:102
3 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw tokenHisKA:202:2.76e-18:268:67:64
4 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw tokenHATPase_c:319:3.5e-30:422:104:109
  • Raw architecture: HAMP:6:0.000000244:74:69:69#PAS_9:96:0.00000117:195:103:102#HisKA:202:2.76e-18:268:67:64#HATPase_c:319:3.5e-30:422:104:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002301035::NZ_MOPD01000014.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span34167-36177Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGU03_14500RefSeq proteinWP_003426968.1
Context group IDGCF_002301035::NZ_MOPD01000014.1::G00046
Context members
BGU03_RS14670BGU03_RS14675
Partner locus tags
BGU03_RS14670BGU03_RS14675
Partner old locus tags
BGU03_14500BGU03_14505
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426968.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NE71Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NE71_CLODCDisplay identifier provided by UniProt.
GO / PubMed6 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGU03_RS14670Primary locus identifier stored in the genes table.
Old locus tagBGU03_14500Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MOPD01000014.1Sequence record reported by the local genomic context database.
Genomic interval34 167-35 456 nt1 290 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span34 167-36 177 ntGCF_002301035::NZ_MOPD01000014.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002301035::NZ_MOPD01000014.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MOPD01000014.1All displayed genes belong to this local TCS context.
Neighborhood span34 167-36 177 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
34 167 nt36 177 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGU03_RS14670GCF_002301035#BGU03_RS14670
HKClassicCurrent focus

34 167-35 456 nt · Reverse (-)

Old locus BGU03_14500RefSeq WP_003426968.1
BGU03_RS14675GCF_002301035#BGU03_RS14675
RROmpR

35 485-36 177 nt · Reverse (-)

Old locus BGU03_14505RefSeq WP_003416112.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2180212Run 6 · HK · 2508 sequences
Representative sequenceGCF_000003215#QAC_RS0213315Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2180212

Simplified PFAM architecture for HKOC_2180212

PFAM domain coverage: 324 / 429 aa (75.5%)

1 aa429 aa
HAMP: 30-74 aaHAMPPAS: 87-193 aaPASHisKA: 202-267 aaHisKAHATPase_c: 317-422 aaHATPase_c
HAMPPASHisKAHATPase_c
  • Simplified architecture: HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: HAMP[30-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
  • Domain count: 4
  • Matched identifier: HKOC_2180212
  • Positioned domains: HAMP 30-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0213315

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002301035
AssemblyASM230103v1 · Contighaploid
Genome composition4 316 075 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key