Gene detail

BGT95_RS04945

Histidine kinase, Hybrid

Clostridioides difficile · GCF_002300935

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002300935#BGT95_RS04945Stable P2CS identifier used across views.
GenomeGCF_002300935Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484793Run 6 · 33 sequences · id 100% · cov 80%
External referencesWP_021370061.1 · MIST4 BGT95_RS04945RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa852 aa
HisKA: 344-410 aa (67 aa)1HATPase_c: 458-576 aa (119 aa)2Response_reg: 592-696 aa (105 aa)3Response_reg: 731-848 aa (118 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:4.53e-18:410:67:64
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:5.26e-25:576:120:109
3 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw tokenResponse_reg:592:3.18e-22:696:105:111
4 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:5.63e-27:848:118:111
  • Raw architecture: HisKA:344:4.53e-18:410:67:64#HATPase_c:458:5.26e-25:576:120:109#Response_reg:592:3.18e-22:696:105:111#Response_reg:731:5.63e-27:848:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002300935::NZ_MNBP01000005.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span122690-127258Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBGT95_04925RefSeq proteinWP_021370061.1
Context group IDGCF_002300935::NZ_MNBP01000005.1::G00013
Context members
BGT95_RS04945BGT95_RS04955
Partner locus tags
BGT95_RS04945BGT95_RS04955
Partner old locus tags
BGT95_04925BGT95_04935
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021370061.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBGT95_RS04945Primary locus identifier stored in the genes table.
Old locus tagBGT95_04925Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MNBP01000005.1Sequence record reported by the local genomic context database.
Genomic interval122 690-125 248 nt2 559 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span122 690-127 258 ntGCF_002300935::NZ_MNBP01000005.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002300935::NZ_MNBP01000005.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MNBP01000005.1All displayed genes belong to this local TCS context.
Neighborhood span122 690-127 258 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
122 690 nt127 258 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BGT95_RS04945GCF_002300935#BGT95_RS04945
HKHybridCurrent focus

122 690-125 248 nt · Reverse (-)

Old locus BGT95_04925RefSeq WP_021370061.1
BGT95_RS04955GCF_002300935#BGT95_RS04955
RRRpfG

125 618-127 258 nt · Reverse (-)

Old locus BGT95_04935RefSeq WP_009901919.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484793Run 6 · HK · 33 sequences
Representative sequenceGCF_000449025#QCG_RS02785Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484793

Simplified PFAM architecture for HKOC_0484793

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484793
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449025#QCG_RS02785

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002300935
AssemblyASM230093v1 · Contighaploid
Genome composition4 212 055 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 45 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key