Gene detail

A7683_RS24730

Histidine kinase, Classic

Escherichia coli · GCF_002227375

ClassHKTypeClassicLength465 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002227375#A7683_RS24730Stable P2CS identifier used across views.
GenomeGCF_002227375Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1772879Run 6 · 4703 sequences · id 100% · cov 80%
External referencesWP_001211892.1 · A0ABD7FFT5 · MIST4 A7683_RS24730RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length465 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 465 aa (36.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa465 aa
HisKA: 244-306 aa (63 aa)1HATPase_c: 352-458 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
244-306 aa · 63 aa · 13.5% of protein
Raw tokenHisKA:244:0.000000000000644:306:63:64
2 HATPase_c#2
352-458 aa · 107 aa · 23.0% of protein
Raw tokenHATPase_c:352:7.94e-34:458:110:109
  • Raw architecture: HisKA:244:0.000000000000644:306:63:64#HATPase_c:352:7.94e-34:458:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002227375::NZ_NLJT01000045.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3485-6204Genomic interval covered by the local TCS group.
Context group IDGCF_002227375::NZ_NLJT01000045.1::G00025
Context members
A7683_RS24725A7683_RS24730
Partner locus tags
A7683_RS24725A7683_RS24730
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001211892.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD7FFT5Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD7FFT5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA7683_RS24730Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_NLJT01000045.1Sequence record reported by the local genomic context database.
Genomic interval4 807-6 204 nt1 398 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 485-6 204 ntGCF_002227375::NZ_NLJT01000045.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002227375::NZ_NLJT01000045.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NLJT01000045.1All displayed genes belong to this local TCS context.
Neighborhood span3 485-6 204 nt2 720 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 485 nt6 204 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1772879Run 6 · HK · 4703 sequences
Representative sequenceGCF_000005845#b4003Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1772879

Simplified PFAM architecture for HKOC_1772879

PFAM domain coverage: 168 / 465 aa (36.1%)

1 aa465 aa
HisKA: 245-307 aaHisKAHATPase_c: 353-457 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-307] | HATPase_c[353-457]
  • Domain count: 2
  • Matched identifier: HKOC_1772879
  • Positioned domains: HisKA 245-307 ; HATPase_c 353-457
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b4003

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_002227375
AssemblyASM222737v1 · Contighaploid
Genome composition5 008 394 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 59 · HK 29 · RR 30CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key