1 HAMP#1
184-251 aa · 68 aa · 14.3% of protein
Raw token
HAMP:184:0.00000000023:251:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
A7683_RS10235
Histidine kinase, Classic
Escherichia coli · GCF_002227375
ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002227375#A7683_RS10235Stable P2CS identifier used across views.
GenomeGCF_002227375Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 474 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
Domain-by-domain annotation3 items
2 HisKA#2
257-319 aa · 63 aa · 13.3% of protein
Raw token
HisKA:257:0.000000000000464:319:63:643 HATPase_c#3
365-469 aa · 105 aa · 22.2% of protein
Raw token
HATPase_c:365:5.49e-24:469:105:109- Raw architecture: HAMP:184:0.00000000023:251:68:69#HisKA:257:0.000000000000464:319:63:64#HATPase_c:365:5.49e-24:469:105:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002227375::NZ_NLJT01000008.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span19044-21157Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_002227375::NZ_NLJT01000008.1::G00035Context members
A7683_RS10235A7683_RS10240
Partner locus tags
A7683_RS10235A7683_RS10240
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001219577.1Primary protein accession used for annex mappings.
UniProt accessionA0A828UFN0Primary UniProt accession resolved in the annex database.
UniProt IDA0A828UFN0_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagA7683_RS10235Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_NLJT01000008.1Sequence record reported by the local genomic context database.
Genomic interval19 044-20 468 nt1 425 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span19 044-21 157 ntGCF_002227375::NZ_NLJT01000008.1::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002227375::NZ_NLJT01000008.1::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NLJT01000008.1All displayed genes belong to this local TCS context.
Neighborhood span19 044-21 157 nt2 114 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
19 044 nt21 157 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
A7683_RS10235GCF_002227375#A7683_RS10235
HKClassicCurrent focus
19 044-20 468 nt · Reverse (-)
A7683_RS10240GCF_002227375#A7683_RS10240
RROmpR
20 468-21 157 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1674072
Simplified PFAM architecture for HKOC_1674072
PFAM domain coverage: 217 / 474 aa (45.8%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[202-251] | HisKA[258-319] | HATPase_c[365-469]
- Domain count: 3
- Matched identifier: HKOC_1674072
- Positioned domains: HAMP 202-251 ; HisKA 258-319 ; HATPase_c 365-469
Cluster members and taxonomy
Representative gene: GCF_000005845#b4399
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 562 · GCF_002227375
AssemblyASM222737v1 · Contighaploid
Genome composition5 008 394 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 59 · HK 29 · RR 30CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key