Gene detail

CA214_RS04775

Histidine kinase, Classic

Enterococcus faecium · GCF_002119065

ClassHKTypeClassicLength611 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002119065#CA214_RS04775Stable P2CS identifier used across views.
GenomeGCF_002119065Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1000690Run 6 · 2171 sequences · id 100% · cov 80%
External referencesWP_002294131.1 · A0AAV3GUQ9 · MIST4 CA214_RS04775RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length611 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 611 aa (58.6%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa611 aa
HAMP: 182-251 aa (70 aa)1PAS: 261-368 aa (108 aa)2HisKA: 377-444 aa (68 aa)3HATPase_c: 493-604 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
182-251 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:182:4.57e-18:251:70:69
2 PAS#2
261-368 aa · 108 aa · 17.7% of protein
Raw tokenPAS:261:0.00000000226:368:113:113
3 HisKA#3
377-444 aa · 68 aa · 11.1% of protein
Raw tokenHisKA:377:1.03e-18:444:68:64
4 HATPase_c#4
493-604 aa · 112 aa · 18.3% of protein
Raw tokenHATPase_c:493:1e-31:604:112:109
  • Raw architecture: HAMP:182:4.57e-18:251:70:69#PAS:261:0.00000000226:368:113:113#HisKA:377:1.03e-18:444:68:64#HATPase_c:493:1e-31:604:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002119065::NZ_NETD01000001.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span924781-927325Genomic interval covered by the local TCS group.
Context group IDGCF_002119065::NZ_NETD01000001.1::G00006
Context members
CA214_RS04775CA214_RS04780
Partner locus tags
CA214_RS04775CA214_RS04780
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002294131.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GUQ9Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GUQ9_ENTFCDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCA214_RS04775Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_NETD01000001.1Sequence record reported by the local genomic context database.
Genomic interval924 781-926 616 nt1 836 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span924 781-927 325 ntGCF_002119065::NZ_NETD01000001.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002119065::NZ_NETD01000001.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NETD01000001.1All displayed genes belong to this local TCS context.
Neighborhood span924 781-927 325 nt2 545 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
924 781 nt927 325 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CA214_RS04780GCF_002119065#CA214_RS04780
RROmpR

926 621-927 325 nt · Reverse (-)

RefSeq WP_002288850.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1000690Run 6 · HK · 2171 sequences
Representative sequenceGCF_000157535#EFQG_RS13310Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1000690

Simplified PFAM architecture for HKOC_1000690

PFAM domain coverage: 381 / 611 aa (62.4%)

1 aa611 aa
Cache_WalK: 79-166 aaCache_WalKHAMP: 199-251 aaHAMPPAS: 262-323 aaPASHisKA: 378-444 aaHisKAHATPase_c: 493-603 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[79-166] | HAMP[199-251] | PAS[262-323] | HisKA[378-444] | HATPase_c[493-603]
  • Domain count: 5
  • Matched identifier: HKOC_1000690
  • Positioned domains: Cache_WalK 79-166 ; HAMP 199-251 ; PAS 262-323 ; HisKA 378-444 ; HATPase_c 493-603
Cluster members and taxonomy
Visualization

Representative gene: GCF_000157535#EFQG_RS13310

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_002119065
AssemblyASM211906v1 · Contighaploid
Genome composition3 145 597 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 39 · HK 19 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key