Gene detail

S2E19_RS22180

Histidine kinase, Classic

Bacillus mycoides · GCF_002118175

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002118175#S2E19_RS22180Stable P2CS identifier used across views.
GenomeGCF_002118175Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1858248Run 6 · 24 sequences · id 100% · cov 80%
External referencesWP_016127266.1 · A0AAP8KWP2 · MIST4 S2E19_RS22180RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 458 aa (53.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
HAMP: 165-234 aa (70 aa)1HisKA: 238-304 aa (67 aa)2HATPase_c: 348-457 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw tokenHAMP:165:1.77e-16:234:70:69
2 HisKA#2
238-304 aa · 67 aa · 14.6% of protein
Raw tokenHisKA:238:1.94e-16:304:67:64
3 HATPase_c#3
348-457 aa · 110 aa · 24.0% of protein
Raw tokenHATPase_c:348:1.58e-34:457:110:109
  • Raw architecture: HAMP:165:1.77e-16:234:70:69#HisKA:238:1.94e-16:304:67:64#HATPase_c:348:1.58e-34:457:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002118175::NZ_MRWV01000014.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span50779-52834Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS2E19_01495RefSeq proteinWP_016127266.1
Context group IDGCF_002118175::NZ_MRWV01000014.1::G00014
Context members
S2E19_RS22175S2E19_RS22180
Partner locus tags
S2E19_RS22175S2E19_RS22180
Partner old locus tags
S2E19_01494S2E19_01495
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_016127266.1Primary protein accession used for annex mappings.
UniProt accessionA0AAP8KWP2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAP8KWP2_BACMYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagS2E19_RS22180Primary locus identifier stored in the genes table.
Old locus tagS2E19_01495Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MRWV01000014.1Sequence record reported by the local genomic context database.
Genomic interval51 458-52 834 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span50 779-52 834 ntGCF_002118175::NZ_MRWV01000014.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002118175::NZ_MRWV01000014.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MRWV01000014.1All displayed genes belong to this local TCS context.
Neighborhood span50 779-52 834 nt2 056 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
50 779 nt52 834 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

S2E19_RS22175GCF_002118175#S2E19_RS22175
RROmpR

50 779-51 456 nt · Forward (+)

Old locus S2E19_01494RefSeq WP_002013739.1
S2E19_RS22180GCF_002118175#S2E19_RS22180
HKClassicCurrent focus

51 458-52 834 nt · Forward (+)

Old locus S2E19_01495RefSeq WP_016127266.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858248Run 6 · HK · 24 sequences
Representative sequenceGCF_000003925#BMYCO0001_RS14260Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858248

Simplified PFAM architecture for HKOC_1858248

PFAM domain coverage: 226 / 458 aa (49.3%)

1 aa458 aa
HAMP: 184-233 aaHAMPHisKA: 238-303 aaHisKAHATPase_c: 348-457 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[184-233] | HisKA[238-303] | HATPase_c[348-457]
  • Domain count: 3
  • Matched identifier: HKOC_1858248
  • Positioned domains: HAMP 184-233 ; HisKA 238-303 ; HATPase_c 348-457
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003925#BMYCO0001_RS14260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_002118175
AssemblyASM211817v1 · Contighaploid
Genome composition5 948 174 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 129 · HK 69 · RR 60CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key