Gene detail

S2E19_RS05200

Histidine kinase, Classic

Bacillus mycoides · GCF_002118175

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002118175#S2E19_RS05200Stable P2CS identifier used across views.
GenomeGCF_002118175Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1858247Run 6 · 48 sequences · id 100% · cov 80%
External referencesWP_002168206.1 · R8N3G0 · MIST4 S2E19_RS05200RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 458 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for S2E19_RS05200
Domain-by-domain annotation3 items
1 HAMP#1
165-232 aa · 68 aa · 14.8% of protein
Raw tokenHAMP:165:0.0000000000000026:232:68:69
2 HisKA#2
244-303 aa · 60 aa · 13.1% of protein
Raw tokenHisKA:244:0.00000000000147:303:61:64
3 HATPase_c#3
349-448 aa · 100 aa · 21.8% of protein
Raw tokenHATPase_c:349:2.84e-17:448:103:109
  • Raw architecture: HAMP:165:0.0000000000000026:232:68:69#HisKA:244:0.00000000000147:303:61:64#HATPase_c:349:2.84e-17:448:103:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002118175::NZ_MRWV01000002.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span261184-263200Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS2E19_02337RefSeq proteinWP_002168206.1
Context group IDGCF_002118175::NZ_MRWV01000002.1::G00025
Context members
S2E19_RS05195S2E19_RS05200
Partner locus tags
S2E19_RS05195S2E19_RS05200
Partner old locus tags
S2E19_02336S2E19_02337
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002168206.1Primary protein accession used for annex mappings.
UniProt accessionR8N3G0Primary UniProt accession resolved in the annex database.
UniProt IDR8N3G0_BACCXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagS2E19_RS05200Primary locus identifier stored in the genes table.
Old locus tagS2E19_02337Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MRWV01000002.1Sequence record reported by the local genomic context database.
Genomic interval261 824-263 200 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span261 184-263 200 ntGCF_002118175::NZ_MRWV01000002.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002118175::NZ_MRWV01000002.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MRWV01000002.1All displayed genes belong to this local TCS context.
Neighborhood span261 184-263 200 nt2 017 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
261 184 nt263 200 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

S2E19_RS05195GCF_002118175#S2E19_RS05195
RROmpR

261 184-261 831 nt · Forward (+)

Old locus S2E19_02336RefSeq WP_002168205.1
S2E19_RS05200GCF_002118175#S2E19_RS05200
HKClassicCurrent focus

261 824-263 200 nt · Forward (+)

Old locus S2E19_02337RefSeq WP_002168206.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858247Run 6 · HK · 48 sequences
Representative sequenceGCF_000003925#BMYCO0001_RS12395Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858247

Simplified PFAM architecture for HKOC_1858247

PFAM domain coverage: 206 / 458 aa (45.0%)

1 aa458 aa
HAMP: 182-232 aaHAMPHisKA: 245-303 aaHisKAHATPase_c: 350-445 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[182-232] | HisKA[245-303] | HATPase_c[350-445]
  • Domain count: 3
  • Matched identifier: HKOC_1858247
  • Positioned domains: HAMP 182-232 ; HisKA 245-303 ; HATPase_c 350-445
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003925#BMYCO0001_RS12395

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_002118175
AssemblyASM211817v1 · Contighaploid
Genome composition5 948 174 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 129 · HK 69 · RR 60CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key