Gene detail

DO83_RS12475

Histidine kinase, Classic

Anaerostipes hadrus · GCF_001998765

ClassHKTypeClassicLength820 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001998765#DO83_RS12475Stable P2CS identifier used across views.
GenomeGCF_001998765Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0529825Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_077327026.1 · A0A1Q2C946 · MIST4 DO83_RS12475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length820 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage610 / 820 aa (74.4%)Merged over positioned domains only.
Domain description2 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa820 aa
SBP_bac_3: 44-260 aa (217 aa)1SBP_bac_3: 282-486 aa (205 aa)2HisKA: 571-639 aa (69 aa)3HATPase_c: 685-803 aa (119 aa)4
Domain-by-domain annotation4 items
1 SBP_bac_3#1
44-260 aa · 217 aa · 26.5% of protein
Raw tokenSBP_bac_3:44:2.2e-32:260:227:224
2 SBP_bac_3#2
282-486 aa · 205 aa · 25.0% of protein
Raw tokenSBP_bac_3:282:0.000000000000115:486:220:224
3 HisKA#3
571-639 aa · 69 aa · 8.4% of protein
Raw tokenHisKA:571:1.29e-18:639:69:64
4 HATPase_c#4
685-803 aa · 119 aa · 14.5% of protein
Raw tokenHATPase_c:685:2.41e-30:803:119:109
  • Raw architecture: SBP_bac_3:44:2.2e-32:260:227:224#SBP_bac_3:282:0.000000000000115:486:220:224#HisKA:571:1.29e-18:639:69:64#HATPase_c:685:2.41e-30:803:119:109
  • Domain description: 2 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001998765::NZ_CP012098.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2484723-2487639Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDO83_12225RefSeq proteinWP_077327026.1
Context group IDGCF_001998765::NZ_CP012098.1::G00032
Context members
DO83_RS12475DO83_RS16535
Partner locus tags
DO83_RS12475DO83_RS16535
Partner old locus tags
DO83_12225
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_077327026.1Primary protein accession used for annex mappings.
UniProt accessionA0A1Q2C946Primary UniProt accession resolved in the annex database.
UniProt IDA0A1Q2C946_ANAHADisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDO83_RS12475Primary locus identifier stored in the genes table.
Old locus tagDO83_12225Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012098.1Sequence record reported by the local genomic context database.
Genomic interval2 484 723-2 487 185 nt2 463 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 484 723-2 487 639 ntGCF_001998765::NZ_CP012098.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001998765::NZ_CP012098.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012098.1All displayed genes belong to this local TCS context.
Neighborhood span2 484 723-2 487 639 nt2 917 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 484 723 nt2 487 639 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DO83_RS12475GCF_001998765#DO83_RS12475
HKClassicCurrent focus

2 484 723-2 487 185 nt · Forward (+)

Old locus DO83_12225RefSeq WP_077327026.1
DO83_RS16535GCF_001998765#DO83_RS16535
RRCheY

2 487 148-2 487 639 nt · Forward (+)

RefSeq WP_242950121.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0529825Run 6 · HK · 2 sequences
Representative sequenceGCF_001998765#DO83_RS12475The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0529825

Simplified PFAM architecture for HKOC_0529825

PFAM domain coverage: 401 / 820 aa (48.9%)

1 aa820 aa
SBP_bac_3: 45-260 aaSBP_bac_3HisKA: 571-639 aaHisKAHATPase_c: 686-801 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[45-260] | HisKA[571-639] | HATPase_c[686-801]
  • Domain count: 3
  • Matched identifier: HKOC_0529825
  • Positioned domains: SBP_bac_3 45-260 ; HisKA 571-639 ; HATPase_c 686-801
Cluster members and taxonomy
Visualization

Representative gene: GCF_001998765#DO83_RS12475

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_001998765
AssemblyASM199876v1 · Complete Genomehaploid
Genome composition3 172 613 bp · 37,5% GCAnaerostipes hadrus
Signal transduction countsGenes 67 · HK 34 · RR 32CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key