Gene detail

DO83_RS08565

Histidine kinase, Classic

Anaerostipes hadrus · GCF_001998765

ClassHKTypeClassicLength658 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001998765#DO83_RS08565Stable P2CS identifier used across views.
GenomeGCF_001998765Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0876870Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_077326530.1 · A0A1Q2C794 · MIST4 DO83_RS08565RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAF_3HisKAHATPase_c
Protein length658 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage302 / 658 aa (45.9%)Merged over positioned domains only.
Domain description1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa658 aa
GAF_3: 291-411 aa (121 aa)1HisKA: 431-498 aa (68 aa)2HATPase_c: 541-653 aa (113 aa)3
Domain-by-domain annotation3 items
1 GAF_3#1
291-411 aa · 121 aa · 18.4% of protein
Raw tokenGAF_3:291:0.0000058:411:126:129
2 HisKA#2
431-498 aa · 68 aa · 10.3% of protein
Raw tokenHisKA:431:0.00000000000223:498:68:64
3 HATPase_c#3
541-653 aa · 113 aa · 17.2% of protein
Raw tokenHATPase_c:541:6.43e-28:653:113:109
  • Raw architecture: GAF_3:291:0.0000058:411:126:129#HisKA:431:0.00000000000223:498:68:64#HATPase_c:541:6.43e-28:653:113:109
  • Domain description: 1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001998765::NZ_CP012098.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1691757-1694424Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDO83_08370RefSeq proteinWP_077326530.1
Context group IDGCF_001998765::NZ_CP012098.1::G00021
Context members
DO83_RS08565DO83_RS08570
Partner locus tags
DO83_RS08565DO83_RS08570
Partner old locus tags
DO83_08370DO83_08375
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_077326530.1Primary protein accession used for annex mappings.
UniProt accessionA0A1Q2C794Primary UniProt accession resolved in the annex database.
UniProt IDA0A1Q2C794_ANAHADisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDO83_RS08565Primary locus identifier stored in the genes table.
Old locus tagDO83_08370Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012098.1Sequence record reported by the local genomic context database.
Genomic interval1 691 757-1 693 733 nt1 977 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 691 757-1 694 424 ntGCF_001998765::NZ_CP012098.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001998765::NZ_CP012098.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012098.1All displayed genes belong to this local TCS context.
Neighborhood span1 691 757-1 694 424 nt2 668 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 691 757 nt1 694 424 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DO83_RS08565GCF_001998765#DO83_RS08565
HKClassicCurrent focus

1 691 757-1 693 733 nt · Forward (+)

Old locus DO83_08370RefSeq WP_077326530.1
DO83_RS08570GCF_001998765#DO83_RS08570
RROmpR

1 693 726-1 694 424 nt · Forward (+)

Old locus DO83_08375RefSeq WP_008392170.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0876870Run 6 · HK · 4 sequences
Representative sequenceGCF_001998765#DO83_RS08565The current gene is the representative for this cluster.
PFAM architectureDUF4118 + GAF_3 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0876870

Simplified PFAM architecture for HKOC_0876870

PFAM domain coverage: 383 / 658 aa (58.2%)

1 aa658 aa
DUF4118: 162-268 aaDUF4118GAF_3: 291-387 aaGAF_3HisKA: 431-498 aaHisKAHATPase_c: 542-652 aaHATPase_c
DUF4118GAF_3HisKAHATPase_c
  • Simplified architecture: DUF4118 + GAF_3 + HisKA + HATPase_c
  • Raw architecture: DUF4118[162-268] | GAF_3[291-387] | HisKA[431-498] | HATPase_c[542-652]
  • Domain count: 4
  • Matched identifier: HKOC_0876870
  • Positioned domains: DUF4118 162-268 ; GAF_3 291-387 ; HisKA 431-498 ; HATPase_c 542-652
Cluster members and taxonomy
Visualization

Representative gene: GCF_001998765#DO83_RS08565

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_001998765
AssemblyASM199876v1 · Complete Genomehaploid
Genome composition3 172 613 bp · 37,5% GCAnaerostipes hadrus
Signal transduction countsGenes 67 · HK 34 · RR 32CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key