Gene detail

BER37_RS03950

Histidine kinase, Classic

Clostridioides difficile · GCF_001972195

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001972195#BER37_RS03950Stable P2CS identifier used across views.
GenomeGCF_001972195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737723Run 6 · 242 sequences · id 100% · cov 80%
External referencesWP_021387636.1 · A0A9P4DAW6 · MIST4 BER37_RS03950RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
HisKA: 245-309 aa (65 aa)1HATPase_c: 357-466 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.00000000000164:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:9.96e-19:466:111:109
  • Raw architecture: HisKA:245:0.00000000000164:309:65:64#HATPase_c:357:9.96e-19:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001972195::NZ_MTWI01000001.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span789916-792074Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBER37_000771RefSeq proteinWP_021387636.1
Context group IDGCF_001972195::NZ_MTWI01000001.1::G00014
Context members
BER37_RS03945BER37_RS03950
Partner locus tags
BER37_RS03945BER37_RS03950
Partner old locus tags
BER37_000770BER37_000771
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021387636.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAW6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAW6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBER37_RS03950Primary locus identifier stored in the genes table.
Old locus tagBER37_000771Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTWI01000001.1Sequence record reported by the local genomic context database.
Genomic interval790 668-792 074 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span789 916-792 074 ntGCF_001972195::NZ_MTWI01000001.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001972195::NZ_MTWI01000001.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTWI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span789 916-792 074 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
789 916 nt792 074 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BER37_RS03945GCF_001972195#BER37_RS03945
RROmpR

789 916-790 623 nt · Forward (+)

Old locus BER37_000770RefSeq WP_021387635.1
BER37_RS03950GCF_001972195#BER37_RS03950
HKClassicCurrent focus

790 668-792 074 nt · Forward (+)

Old locus BER37_000771RefSeq WP_021387636.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737723Run 6 · HK · 242 sequences
Representative sequenceGCF_000210395#CDM68_RS03685Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737723

Simplified PFAM architecture for HKOC_1737723

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737723
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS03685

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001972195
AssemblyASM197219v1 · Contighaploid
Genome composition4 278 990 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key