Gene detail

BER44_RS04645

Histidine kinase, Classic

Clostridioides difficile · GCF_001972185

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001972185#BER44_RS04645Stable P2CS identifier used across views.
GenomeGCF_001972185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1738099Run 6 · 158 sequences · id 100% · cov 80%
External referencesWP_021367592.1 · MIST4 BER44_RS04645RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BER44_RS04645
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.00000000000219:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:9.73e-18:466:111:109
  • Raw architecture: HisKA:245:0.00000000000219:309:65:64#HATPase_c:357:9.73e-18:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001972185::NZ_MTWH01000003.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span632739-634897Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBER44_000928RefSeq proteinWP_021367592.1
Context group IDGCF_001972185::NZ_MTWH01000003.1::G00013
Context members
BER44_RS04640BER44_RS04645
Partner locus tags
BER44_RS04640BER44_RS04645
Partner old locus tags
BER44_000927BER44_000928
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021367592.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBER44_RS04645Primary locus identifier stored in the genes table.
Old locus tagBER44_000928Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTWH01000003.1Sequence record reported by the local genomic context database.
Genomic interval633 491-634 897 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span632 739-634 897 ntGCF_001972185::NZ_MTWH01000003.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001972185::NZ_MTWH01000003.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTWH01000003.1All displayed genes belong to this local TCS context.
Neighborhood span632 739-634 897 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
632 739 nt634 897 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BER44_RS04640GCF_001972185#BER44_RS04640
RROmpR

632 739-633 446 nt · Forward (+)

Old locus BER44_000927RefSeq WP_009888460.1
BER44_RS04645GCF_001972185#BER44_RS04645
HKClassicCurrent focus

633 491-634 897 nt · Forward (+)

Old locus BER44_000928RefSeq WP_021367592.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1738099Run 6 · HK · 158 sequences
Representative sequenceGCF_000448805#QKI_RS03780Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1738099

Simplified PFAM architecture for HKOC_1738099

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1738099
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS03780

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001972185
AssemblyASM197218v1 · Contighaploid
Genome composition4 469 133 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key