Gene detail

BER35_RS18395

Histidine kinase, Classic

Clostridioides difficile · GCF_001972065

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001972065#BER35_RS18395Stable P2CS identifier used across views.
GenomeGCF_001972065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503304Run 6 · 294 sequences · id 100% · cov 80%
External referencesWP_003422313.1 · D5Q9X2 · MIST4 BER35_RS18395RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 168-234 aa (67 aa)1HATPase_c: 280-388 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw tokenHisKA:168:0.000000000000401:234:67:64
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw tokenHATPase_c:280:4.98e-26:388:110:109
  • Raw architecture: HisKA:168:0.000000000000401:234:67:64#HATPase_c:280:4.98e-26:388:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001972065::NZ_MTWE01000004.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3607906-3609769Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBER35_003623RefSeq proteinWP_003422313.1
Context group IDGCF_001972065::NZ_MTWE01000004.1::G00054
Context members
BER35_RS18395BER35_RS18400
Partner locus tags
BER35_RS18395BER35_RS18400
Partner old locus tags
BER35_003623BER35_003624
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003422313.1Primary protein accession used for annex mappings.
UniProt accessionD5Q9X2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q9X2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBER35_RS18395Primary locus identifier stored in the genes table.
Old locus tagBER35_003623Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTWE01000004.1Sequence record reported by the local genomic context database.
Genomic interval3 607 906-3 609 087 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 607 906-3 609 769 ntGCF_001972065::NZ_MTWE01000004.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001972065::NZ_MTWE01000004.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTWE01000004.1All displayed genes belong to this local TCS context.
Neighborhood span3 607 906-3 609 769 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 607 906 nt3 609 769 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BER35_RS18395GCF_001972065#BER35_RS18395
HKClassicCurrent focus

3 607 906-3 609 087 nt · Reverse (-)

Old locus BER35_003623RefSeq WP_003422313.1
BER35_RS18400GCF_001972065#BER35_RS18400
RROmpR

3 609 077-3 609 769 nt · Reverse (-)

Old locus BER35_003624RefSeq WP_003422314.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503304Run 6 · HK · 294 sequences
Representative sequenceGCF_000155065#QAE_RS0217715Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503304

Simplified PFAM architecture for HKOC_2503304

PFAM domain coverage: 175 / 393 aa (44.5%)

1 aa393 aa
HisKA: 168-233 aaHisKAHATPase_c: 281-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[168-233] | HATPase_c[281-389]
  • Domain count: 2
  • Matched identifier: HKOC_2503304
  • Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0217715

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 294 total members. Page 1 / 6.

GCF_000155065#QAE_RS0217715 (representative)
QAE_RS0217715 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_000164175#HMPREF0220_RS02715
HMPREF0220_RS02715 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_000164655#HMPREF0219_RS12975
HMPREF0219_RS12975 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_000210435#CDM120_RS18110
CDM120_RS18110 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_000499505#BN164_RS16780
BN164_RS16780 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_000582865#BN165_RS17400
BN165_RS17400 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_001050575#BN163_RS17710
BN163_RS17710 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_001972065#BER35_RS18395
BER35_RS18395 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_001972115#BER34_RS04070
BER34_RS04070 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002301695#BGU20_RS09750
BGU20_RS09750 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002302685#BGU93_RS17685
BGU93_RS17685 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002303305#BGU53_RS12770
BGU53_RS12770 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002303425#BGU60_RS05170
BGU60_RS05170 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002352505#V439_RS05450
V439_RS05450 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002412385#V438_RS10585
V438_RS10585 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002946515#C4E25_RS18730
C4E25_RS18730 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002946535#C4E42_RS00455
C4E42_RS00455 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_002946555#C4E26_RS18730
C4E26_RS18730 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_003482165#CDIF29020_RS19080
CDIF29020_RS19080 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_003482365#CDIF29747_RS18600
CDIF29747_RS18600 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_003697205#EBB60_RS18485
EBB60_RS18485 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_003697225#EBL90_RS18630
EBL90_RS18630 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_003697245#EBL91_RS18235
EBL91_RS18235 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_004318565#E0Q96_RS11815
E0Q96_RS11815 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_004318785#E0Q93_RS13535
E0Q93_RS13535 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_008579085#F6C11_RS09810
F6C11_RS09810 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_009362915#FTB24_RS00450
FTB24_RS00450 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_012952655#HCN89_RS18900
HCN89_RS18900 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_015351855#ITI91_RS18105
ITI91_RS18105 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_015352255#ITJ05_RS01325
ITJ05_RS01325 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016766955#JMW53_RS07405
JMW53_RS07405 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016766975#JMW50_RS14740
JMW50_RS14740 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016766995#JMW52_RS02375
JMW52_RS02375 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016767015#JMW49_RS08755
JMW49_RS08755 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016767035#JMW55_RS05700
JMW55_RS05700 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016767055#JMW51_RS02995
JMW51_RS02995 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016767095#JMW48_RS15345
JMW48_RS15345 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016767115#JMW47_RS11805
JMW47_RS11805 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_016767135#JMW46_RS09180
JMW46_RS09180 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_017592625#J5O10_RS18255
J5O10_RS18255 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_018603395#KK111_RS17835
KK111_RS17835 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_018603455#KK110_RS17830
KK110_RS17830 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_018603475#KK112_RS17790
KK112_RS17790 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_018884725#E1H40_RS17520
E1H40_RS17520 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_019427665#K1N48_RS08440
K1N48_RS08440 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_019427725#K1N54_RS10530
K1N54_RS10530 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_020297505#LA365_RS05305
LA365_RS05305 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_021283625#LWE91_RS07590
LWE91_RS07590 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_021283665#LWF03_RS09485
LWF03_RS09485 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2
GCF_021283685#LWE71_RS03605
LWE71_RS03605 · HK · Classic
RefSeq: WP_003422313.1
UniProt: D5Q9X2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001972065
AssemblyASM197206v1 · Contighaploid
Genome composition4 057 973 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key