Gene detail

BER28_RS13460

Histidine kinase, Classic

Clostridioides difficile · GCF_001971835

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001971835#BER28_RS13460Stable P2CS identifier used across views.
GenomeGCF_001971835Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440521Run 6 · 373 sequences · id 100% · cov 80%
External referencesWP_009890816.1 · A0A0H3N4N9 · MIST4 BER28_RS13460RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:2.6e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.00000000146:400:108:109
  • Raw architecture: His_kinase:205:2.6e-31:283:80:80#HATPase_c:300:0.00000000146:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001971835::NZ_MTVP01000004.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2693949-2695926Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBER28_002645RefSeq proteinWP_009890816.1
Context group IDGCF_001971835::NZ_MTVP01000004.1::G00042
Context members
BER28_RS13455BER28_RS13460
Partner locus tags
BER28_RS13455BER28_RS13460
Partner old locus tags
BER28_002644BER28_002645
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009890816.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4N9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4N9_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBER28_RS13460Primary locus identifier stored in the genes table.
Old locus tagBER28_002645Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTVP01000004.1Sequence record reported by the local genomic context database.
Genomic interval2 694 724-2 695 926 nt1 203 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 693 949-2 695 926 ntGCF_001971835::NZ_MTVP01000004.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001971835::NZ_MTVP01000004.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTVP01000004.1All displayed genes belong to this local TCS context.
Neighborhood span2 693 949-2 695 926 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 693 949 nt2 695 926 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BER28_RS13455GCF_001971835#BER28_RS13455
RRLytTR

2 693 949-2 694 719 nt · Reverse (-)

Old locus BER28_002644RefSeq WP_009890815.1
BER28_RS13460GCF_001971835#BER28_RS13460
HKClassicCurrent focus

2 694 724-2 695 926 nt · Reverse (-)

Old locus BER28_002645RefSeq WP_009890816.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440521Run 6 · HK · 373 sequences
Representative sequenceGCF_000003215#QAC_RS0213135Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440521

Simplified PFAM architecture for HKOC_2440521

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440521
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0213135

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 373 total members. Page 1 / 8.

GCF_000003215#QAC_RS0213135 (representative)
QAC_RS0213135 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000027105#CDR20291_RS13495
CDR20291_RS13495 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000085225#CD196_RS13215
CD196_RS13215 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000154645#UAA_RS0215025
UAA_RS0215025 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000154665#QAD_RS0213290
QAD_RS0213290 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000154685#AEC_RS0214620
AEC_RS0214620 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000155045#EAA_RS0213045
EAA_RS0213045 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000210455#CD7855_RS13000
CD7855_RS13000 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000211235#CDBI1_RS13090
CDBI1_RS13090 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000450765#QO5_RS13825
QO5_RS13825 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000450785#QO7_RS13385
QO7_RS13385 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000451065#QSC_RS12850
QSC_RS12850 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000451785#QSO_RS12840
QSO_RS12840 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000451885#QU5_RS12920
QU5_RS12920 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000530795#BN175_RS13100
BN175_RS13100 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000531785#BN176_RS12835
BN176_RS12835 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_000826625#BN2378_RS02460
BN2378_RS02460 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_001484885#CD26A54R_RS13035
CD26A54R_RS13035 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_001484895#CD26A54S_RS13150
CD26A54S_RS13150 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_001857645#HMPREF3082_RS09945
HMPREF3082_RS09945 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_001971835#BER28_RS13460
BER28_RS13460 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_001971865#BER27_RS13915
BER27_RS13915 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_001972015#BER29_RS13405
BER29_RS13405 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002301465#BGU24_RS06970
BGU24_RS06970 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002301525#BGU28_RS14360
BGU28_RS14360 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002301615#BGU34_RS12325
BGU34_RS12325 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002301715#BGU39_RS10415
BGU39_RS10415 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002301945#BGU80_RS03730
BGU80_RS03730 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002302765#BGV01_RS09240
BGV01_RS09240 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002302845#BGV07_RS09295
BGV07_RS09295 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002303105#BGV21_RS08445
BGV21_RS08445 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002303165#BGV24_RS03230
BGV24_RS03230 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002335485#NCKUH21_RS12870
NCKUH21_RS12870 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002812585#CWR57_RS12845
CWR57_RS12845 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002945415#C3W74_RS13520
C3W74_RS13520 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002945515#C3L34_RS14005
C3L34_RS14005 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002945665#C3347_RS13520
C3347_RS13520 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002945755#C3348_RS13525
C3348_RS13525 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002945855#C3350_RS13535
C3350_RS13535 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002945945#C3349_RS13525
C3349_RS13525 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002946035#C3351_RS13530
C3351_RS13530 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002946135#C3352_RS13530
C3352_RS13530 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002946195#C3353_RS13520
C3353_RS13520 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002954285#AMR92_RS05390
AMR92_RS05390 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_002954305#AMR91_RS16195
AMR91_RS16195 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_003313545#CDIF27638_RS13535
CDIF27638_RS13535 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_003313585#CDIF27640_RS13525
CDIF27640_RS13525 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_003482035#CDIF28196_RS13600
CDIF28196_RS13600 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_003597795#DA426_RS06380
DA426_RS06380 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9
GCF_003597815#DA430_RS13530
DA430_RS13530 · HK · Classic
RefSeq: WP_009890816.1
UniProt: A0A0H3N4N9

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001971835
AssemblyASM197183v1 · Contighaploid
Genome composition4 189 946 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key