Gene detail

BW27_RS01475

Histidine kinase, Classic

Clostridioides difficile · GCF_001757625

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_001757625#BW27_RS01475Stable P2CS identifier used across views.
GenomeGCF_001757625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842488Run 6 · 250 sequences · id 100% · cov 80%
External referencesWP_021427717.1 · A0A9P4DA33 · MIST4 BW27_RS01475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000611:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:1e-28:668:104:109
  • Raw architecture: HisKA:449:0.00000000611:514:66:64#HATPase_c:565:1e-28:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_001757625::NZ_JFOG01000005.1::G00038
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span140141-145865Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW27_14670RefSeq proteinWP_021427717.1
Context group IDGCF_001757625::NZ_JFOG01000005.1::G00038
Context members
BW27_RS01460BW27_RS01465BW27_RS01470BW27_RS01475BW27_RS01480
Partner locus tags
BW27_RS01460BW27_RS01465BW27_RS01470BW27_RS01475BW27_RS01480
Partner old locus tags
BW27_14655BW27_14660BW27_14665BW27_14670BW27_14675

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021427717.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DA33Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DA33_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBW27_RS01475Primary locus identifier stored in the genes table.
Old locus tagBW27_14670Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOG01000005.1Sequence record reported by the local genomic context database.
Genomic interval143 101-145 116 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span140 141-145 865 ntGCF_001757625::NZ_JFOG01000005.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757625::NZ_JFOG01000005.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOG01000005.1All displayed genes belong to this local TCS context.
Neighborhood span140 141-145 865 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
140 141 nt145 865 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

BW27_RS01460GCF_001757625#BW27_RS01460
HKClassic

140 141-141 256 nt · Reverse (-)

Old locus BW27_14655RefSeq WP_021388285.1
BW27_RS01465GCF_001757625#BW27_RS01465
RROmpR

141 292-141 990 nt · Reverse (-)

Old locus BW27_14660RefSeq WP_003432359.1
BW27_RS01470GCF_001757625#BW27_RS01470
RROmpR

142 371-143 051 nt · Reverse (-)

Old locus BW27_14665RefSeq WP_070116814.1
BW27_RS01475GCF_001757625#BW27_RS01475
HKClassicCurrent focus

143 101-145 116 nt · Reverse (-)

Old locus BW27_14670RefSeq WP_021427717.1
BW27_RS01480GCF_001757625#BW27_RS01480
RROmpR

145 188-145 865 nt · Reverse (-)

Old locus BW27_14675RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842488Run 6 · HK · 250 sequences
Representative sequenceGCF_000210395#CDM68_RS16915Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842488

Simplified PFAM architecture for HKOC_0842488

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842488
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS16915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757625
AssemblyASM175762v1 · Contighaploid
Genome composition4 180 898 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key