Gene detail

BM72_RS03995

Histidine kinase, Classic

Clostridioides difficile · GCF_001757615

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757615#BM72_RS03995Stable P2CS identifier used across views.
GenomeGCF_001757615Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440987Run 6 · 78 sequences · id 100% · cov 80%
External referencesWP_021422548.1 · MIST4 BM72_RS03995RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:2.79e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.00000000135:400:108:109
  • Raw architecture: His_kinase:205:2.79e-31:283:80:80#HATPase_c:300:0.00000000135:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001757615::NZ_JFOI01000014.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span134019-135996Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBM72_01145RefSeq proteinWP_021422548.1
Context group IDGCF_001757615::NZ_JFOI01000014.1::G00007
Context members
BM72_RS03995BM72_RS04000
Partner locus tags
BM72_RS03995BM72_RS04000
Partner old locus tags
BM72_01145BM72_01150
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021422548.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBM72_RS03995Primary locus identifier stored in the genes table.
Old locus tagBM72_01145Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOI01000014.1Sequence record reported by the local genomic context database.
Genomic interval134 019-135 221 nt1 203 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span134 019-135 996 ntGCF_001757615::NZ_JFOI01000014.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757615::NZ_JFOI01000014.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOI01000014.1All displayed genes belong to this local TCS context.
Neighborhood span134 019-135 996 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
134 019 nt135 996 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BM72_RS03995GCF_001757615#BM72_RS03995
HKClassicCurrent focus

134 019-135 221 nt · Forward (+)

Old locus BM72_01145RefSeq WP_021422548.1
BM72_RS04000GCF_001757615#BM72_RS04000
RRLytTR

135 226-135 996 nt · Forward (+)

Old locus BM72_01150RefSeq WP_021423519.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440987Run 6 · HK · 78 sequences
Representative sequenceGCF_000451765#QSM_RS05420Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440987

Simplified PFAM architecture for HKOC_2440987

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440987
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451765#QSM_RS05420

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757615
AssemblyASM175761v1 · Contighaploid
Genome composition4 138 192 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key